Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   CO204_RS07940 Genome accession   NZ_CP023477
Coordinates   1562795..1564096 (-) Length   433 a.a.
NCBI ID   WP_106006809.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1557795..1569096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS07915 (CO204_07880) - 1557853..1558488 (+) 636 WP_019321473.1 hypothetical protein -
  CO204_RS07920 (CO204_07885) - 1558568..1560268 (-) 1701 WP_019803194.1 zinc ribbon domain-containing protein -
  CO204_RS07925 (CO204_07890) - 1560288..1561382 (-) 1095 WP_002266342.1 hypothetical protein -
  CO204_RS07930 (CO204_07895) raiA 1561506..1562054 (-) 549 WP_002263024.1 ribosome-associated translation inhibitor RaiA -
  CO204_RS07935 (CO204_07900) - 1562133..1562798 (-) 666 WP_106006808.1 ComF family protein -
  CO204_RS07940 (CO204_07905) comFA/cflA 1562795..1564096 (-) 1302 WP_106006809.1 DEAD/DEAH box helicase Machinery gene
  CO204_RS07945 (CO204_07910) - 1564169..1564798 (+) 630 WP_002272858.1 YigZ family protein -
  CO204_RS07950 (CO204_07915) cysK 1564889..1565815 (+) 927 WP_106006810.1 cysteine synthase A -
  CO204_RS07955 (CO204_07920) - 1566149..1567240 (-) 1092 WP_002263029.1 glycerol dehydrogenase -
  CO204_RS07960 (CO204_07925) - 1567279..1567947 (-) 669 WP_002293872.1 fructose-6-phosphate aldolase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49551.69 Da        Isoelectric Point: 10.0023

>NTDB_id=247436 CO204_RS07940 WP_106006809.1 1562795..1564096(-) (comFA/cflA) [Streptococcus mutans strain LAR01]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLTSILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRGKLPRSFFQQIRIQRQTQYPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=247436 CO204_RS07940 WP_106006809.1 1562795..1564096(-) (comFA/cflA) [Streptococcus mutans strain LAR01]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGACCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGGTAAATTACCGCGCTCTTTTTTTCAGCAGA
TAAGAATTCAAAGGCAGACTCAATACCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACCTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCCTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATTTGTTCACCAAAAGTTCTCTGGTACAGATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-194)

Helicase conserved C-terminal domain (Helicase_C)

(296-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae D39

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae R6

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae TIGR4

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

58.782

98.614

0.58
  comFA/cflA Streptococcus mitis SK321

58.314

98.614

0.575
  comFA Lactococcus lactis subsp. cremoris KW2

51.523

90.993

0.469
  comFA Latilactobacillus sakei subsp. sakei 23K

38.967

98.383

0.383

Multiple sequence alignment