Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AOY72_RS09825 Genome accession   NZ_CP028756
Coordinates   2035714..2036370 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain A19     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2030714..2041370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY72_RS09795 (AOY72_10470) dcyD 2031594..2032580 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  AOY72_RS09800 (AOY72_10475) tcyL 2032595..2033263 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AOY72_RS09805 (AOY72_10480) tcyN 2033260..2034012 (+) 753 WP_201479166.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AOY72_RS09810 (AOY72_10485) sdiA 2034242..2034964 (+) 723 WP_001154285.1 transcriptional regulator SdiA -
  AOY72_RS09815 (AOY72_10490) yecF 2035031..2035255 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AOY72_RS09820 yecU 2035242..2035418 (-) 177 WP_000590347.1 protein YecU -
  AOY72_RS24300 - 2035501..2035572 (-) 72 Protein_1925 transcriptional regulator -
  AOY72_RS09825 (AOY72_10495) letA 2035714..2036370 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AOY72_RS09830 (AOY72_10500) uvrC 2036367..2038199 (+) 1833 WP_171861394.1 excinuclease ABC subunit UvrC Machinery gene
  AOY72_RS09835 (AOY72_10505) pgsA 2038256..2038804 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AOY72_RS09855 (AOY72_10525) yecA 2039454..2040119 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=247197 AOY72_RS09825 WP_000611335.1 2035714..2036370(+) (letA) [Escherichia coli strain A19]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=247197 AOY72_RS09825 WP_000611335.1 2035714..2036370(+) (letA) [Escherichia coli strain A19]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment