Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CNH35_RS02975 Genome accession   NZ_CP023390
Coordinates   570767..571336 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus subsp. aureus str. Newman strain NYU_Newman     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 565767..576336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CNH35_RS02950 (CNH35_02920) cysE 566980..567627 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  CNH35_RS02955 (CNH35_02925) cysS 567611..569011 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  CNH35_RS02960 (CNH35_02930) - 569004..569408 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  CNH35_RS02965 (CNH35_02935) rlmB 569416..570162 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CNH35_RS02970 (CNH35_02940) - 570162..570686 (+) 525 WP_000664738.1 NYN domain-containing protein -
  CNH35_RS02975 (CNH35_02945) sigH 570767..571336 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  CNH35_RS02980 (CNH35_02950) rpmG 571451..571594 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  CNH35_RS02985 (CNH35_02955) secE 571650..571832 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  CNH35_RS02990 (CNH35_02960) nusG 571845..572393 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  CNH35_RS02995 (CNH35_02965) rplK 572574..572996 (+) 423 WP_001085794.1 50S ribosomal protein L11 -
  CNH35_RS03000 (CNH35_02970) rplA 573204..573896 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  CNH35_RS03010 (CNH35_02980) rplJ 574168..574668 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  CNH35_RS03015 (CNH35_02985) rplL 574711..575079 (+) 369 WP_001273585.1 50S ribosomal protein L7/L12 -
  CNH35_RS03020 (CNH35_02990) - 575254..575862 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=246499 CNH35_RS02975 WP_000872873.1 570767..571336(+) (sigH) [Staphylococcus aureus subsp. aureus str. Newman strain NYU_Newman]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=246499 CNH35_RS02975 WP_000872873.1 570767..571336(+) (sigH) [Staphylococcus aureus subsp. aureus str. Newman strain NYU_Newman]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment