Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CLI97_RS16355 Genome accession   NZ_CP023320
Coordinates   3107019..3107675 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SCGB     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3102019..3112675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CLI97_RS16330 (CLI97_03221) oppF 3102548..3103465 (+) 918 WP_070081625.1 oligopeptide ABC transporter ATP-binding protein OppF -
  CLI97_RS16335 (CLI97_03222) - 3103572..3104759 (+) 1188 WP_094247077.1 putative glycoside hydrolase -
  CLI97_RS16340 (CLI97_03223) - 3104877..3105455 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  CLI97_RS16345 (CLI97_03224) spx 3105634..3106029 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  CLI97_RS16350 (CLI97_03225) - 3106087..3106743 (-) 657 WP_003155033.1 TerC family protein -
  CLI97_RS21040 - 3106926..3107036 (+) 111 Protein_3154 adaptor protein MecA -
  CLI97_RS16355 (CLI97_03226) mecA 3107019..3107675 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  CLI97_RS16360 (CLI97_03227) - 3107826..3108986 (+) 1161 WP_094247076.1 competence protein CoiA family protein -
  CLI97_RS16365 (CLI97_03228) pepF 3109214..3111043 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  CLI97_RS21045 (CLI97_03229) - 3111081..3111248 (-) 168 WP_003155026.1 hypothetical protein -
  CLI97_RS16375 (CLI97_03230) spxH 3111534..3112436 (-) 903 WP_024085126.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=246068 CLI97_RS16355 WP_003155032.1 3107019..3107675(+) (mecA) [Bacillus velezensis strain SCGB]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=246068 CLI97_RS16355 WP_003155032.1 3107019..3107675(+) (mecA) [Bacillus velezensis strain SCGB]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment