Detailed information NTG0245922

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: B8B76_RS10805
• Genome accession: NZ_CP023316
• Coordinates: 2287631..2289856 (+)
• Length: 741 a.a.
• NCBI ID: WP_023100928.1
• Uniprot ID: A0A509JMW0
• Organism: Pseudomonas aeruginosa strain PPF-1
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2282631..2294856

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B8B76_RS10775 (B8B76_10750)	-	2282631..2282939 (-)	309	WP_021265003.1	hypothetical protein	-
B8B76_RS10780 (B8B76_10755)	-	2282949..2283548 (-)	600	WP_003091172.1	PilZ domain-containing protein	-
B8B76_RS10785 (B8B76_10760)	-	2283651..2284901 (+)	1251	WP_015502671.1	lipoprotein-releasing ABC transporter permease subunit	-
B8B76_RS10790 (B8B76_10765)	lolD	2284894..2285577 (+)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
B8B76_RS10795 (B8B76_10770)	-	2285647..2286891 (+)	1245	WP_003105198.1	lipoprotein-releasing ABC transporter permease subunit	-
B8B76_RS10800 (B8B76_10775)	-	2286967..2287500 (-)	534	WP_003091165.1	DUF2062 domain-containing protein	-
B8B76_RS10805 (B8B76_10780)	comA	2287631..2289856 (+)	2226	WP_023100928.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
B8B76_RS10810 (B8B76_10785)	exbB	2289929..2290564 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
B8B76_RS10815 (B8B76_10790)	-	2290561..2291001 (+)	441	WP_003091161.1	ExbD/TolR family protein	-
B8B76_RS10820 (B8B76_10795)	lpxK	2291001..2291999 (+)	999	WP_003130692.1	tetraacyldisaccharide 4'-kinase	-
B8B76_RS10825 (B8B76_10800)	-	2292037..2292222 (+)	186	WP_003091157.1	Trm112 family protein	-
B8B76_RS10830 (B8B76_10805)	kdsB	2292222..2292986 (+)	765	WP_003091155.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
B8B76_RS10835 (B8B76_10810)	-	2292986..2293450 (+)	465	WP_003106924.1	low molecular weight protein-tyrosine-phosphatase	-
B8B76_RS10840 (B8B76_10815)	murB	2293447..2294466 (+)	1020	WP_021265002.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79964.54 Da
• Isoelectric Point: 10.5155

>NTDB_id=245922 B8B76_RS10805 WP_023100928.1 2287631..2289856(+) (comA) [Pseudomonas aeruginosa strain PPF-1]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLGTLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHALLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPGWLVSGEPARLPSPLFADSCDERRWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=245922 B8B76_RS10805 WP_023100928.1 2287631..2289856(+) (comA) [Pseudomonas aeruginosa strain PPF-1]
ATGCGCCTGGGATTGCCAGCTCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCAGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCTTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGTGCTTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGGAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCTGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCACTTGGCCTGCTGGCGGGCCTGGCCGAGGCGTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCGTTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGGGAGCATGCCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGGTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGCGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGCGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCGCGGGTCGACTGGTTGCTGGCGCCGCATCACGGCAGCCGCAGCTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAACGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A509JMW0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	59.223	97.301	0.576
comA	Ralstonia pseudosolanacearum GMI1000	35.742	100	0.367