Detailed information NTG0245416

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: YA91_RS11050
• Genome accession: NZ_CP023248
• Coordinates: 581959..582828 (-)
• Length: 289 a.a.
• NCBI ID: WP_005493974.1
• Uniprot ID: A0A249W3M2
• Organism: Vibrio parahaemolyticus strain MAVP-26
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 576959..587828

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
YA91_RS11015 (YA91_11660)	rpsP	577913..578161 (+)	249	WP_005379962.1	30S ribosomal protein S16	-
YA91_RS11020 (YA91_11665)	rimM	578190..578738 (+)	549	WP_005462552.1	ribosome maturation factor RimM	-
YA91_RS11025 (YA91_11670)	trmD	578766..579509 (+)	744	WP_005462562.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
YA91_RS11030 (YA91_11675)	rplS	579551..579904 (+)	354	WP_005462554.1	50S ribosomal protein L19	-
YA91_RS11035 (YA91_11680)	yacG	580313..580507 (-)	195	WP_005462546.1	DNA gyrase inhibitor YacG	-
YA91_RS11040 (YA91_11685)	zapD	580576..581316 (-)	741	WP_005480890.1	cell division protein ZapD	-
YA91_RS11045 (YA91_11690)	coaE	581344..581958 (-)	615	WP_005493969.1	dephospho-CoA kinase	-
YA91_RS11050 (YA91_11695)	pilD	581959..582828 (-)	870	WP_005493974.1	A24 family peptidase	Machinery gene
YA91_RS11055 (YA91_11700)	pilC	582893..584116 (-)	1224	WP_005493981.1	type II secretion system F family protein	Machinery gene
YA91_RS11060 (YA91_11705)	pilB	584140..585825 (-)	1686	WP_005493983.1	type IV-A pilus assembly ATPase PilB	Machinery gene
YA91_RS11065 (YA91_11710)	-	585827..586279 (-)	453	WP_005493986.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
YA91_RS11070 (YA91_11715)	nadC	586543..587430 (-)	888	WP_005493988.1	carboxylating nicotinate-nucleotide diphosphorylase	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32377.43 Da
• Isoelectric Point: 7.1971

>NTDB_id=245416 YA91_RS11050 WP_005493974.1 581959..582828(-) (pilD) [Vibrio parahaemolyticus strain MAVP-26]
MEVFQYYPWLFVVFASIFGLIVGSFLNVVIYRLPKIMELEWRRECAESFPEYKIKPPQEVLTLSVPRSSCQNCATPIRIR
DNIPVISWLLLKGKCHHCHTAISPRYPLIELLTAACAGFVAYHFGFSYFTVALIFFTFVLIAATFIDLDTMLLPDQLTLP
LTWAGIALALTEISPVSLQDAVIGAIAGYLCLWSVYWGFKLLTGKEGMGYGDFKLLAALGAWLGWQSLPMIILLSSVVGV
IFGLVQLRLQKQGIERAFPFGPYLAIAGWASLIWGDQILSWYFTSILGV

Nucleotide

• Length: 870 bp

>NTDB_id=245416 YA91_RS11050 WP_005493974.1 581959..582828(-) (pilD) [Vibrio parahaemolyticus strain MAVP-26]
ATGGAAGTGTTCCAGTACTACCCTTGGCTATTCGTGGTGTTTGCCAGTATCTTCGGTTTAATTGTGGGTAGTTTTCTTAA
TGTAGTCATTTATCGGCTACCTAAAATCATGGAATTAGAATGGCGCCGTGAATGCGCCGAATCATTCCCTGAATATAAGA
TTAAGCCACCTCAAGAAGTTTTGACATTAAGCGTGCCTCGCTCTTCGTGCCAAAACTGCGCGACGCCAATTCGTATTCGA
GACAATATTCCTGTAATCAGCTGGCTACTGTTAAAAGGAAAATGCCATCATTGTCATACCGCAATTAGTCCTCGATATCC
GCTAATAGAATTACTCACTGCAGCGTGCGCTGGTTTTGTGGCTTATCATTTCGGCTTTAGCTACTTTACGGTTGCGTTAA
TCTTTTTCACATTTGTCTTAATAGCCGCGACTTTTATCGATCTCGATACTATGCTGCTACCGGACCAATTAACATTACCA
TTAACTTGGGCTGGCATTGCGTTAGCATTAACAGAAATAAGCCCTGTTAGTCTACAAGACGCCGTAATTGGTGCGATTGC
CGGTTATTTGTGTCTTTGGTCAGTATATTGGGGTTTCAAACTGCTTACTGGTAAAGAAGGCATGGGTTACGGTGATTTTA
AATTGCTGGCTGCCCTTGGCGCTTGGCTAGGATGGCAATCATTACCAATGATCATCCTACTTTCTTCTGTCGTCGGTGTG
ATATTCGGGCTCGTTCAGTTACGACTACAAAAACAAGGTATAGAGAGAGCTTTCCCTTTCGGCCCATATTTAGCGATTGC
AGGATGGGCAAGCTTAATCTGGGGCGATCAAATTCTAAGTTGGTACTTCACGTCAATTTTAGGAGTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (135-244)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

3D structure

• AlphaFold DB: A0A249W3M2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio campbellii strain DS40M4	88.927	100	0.889
pilD	Vibrio cholerae strain A1552	73.611	99.654	0.734
pilD	Acinetobacter baumannii D1279779	52.239	92.734	0.484
pilD	Acinetobacter nosocomialis M2	51.866	92.734	0.481
pilD	Neisseria gonorrhoeae MS11	47.101	95.502	0.45