Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DBA17_RS09340 Genome accession   NZ_CP028719
Coordinates   2228385..2229026 (-) Length   213 a.a.
NCBI ID   WP_128789446.1    Uniprot ID   A0A7W3NLN3
Organism   Streptomyces sp. endophyte_N2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2223385..2234026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DBA17_RS09310 - 2223871..2224377 (+) 507 WP_128789444.1 HNH endonuclease -
  DBA17_RS09315 - 2224497..2225462 (-) 966 WP_037656593.1 SPFH domain-containing protein -
  DBA17_RS09320 - 2225589..2226020 (-) 432 WP_037656595.1 NfeD family protein -
  DBA17_RS09325 - 2226168..2226965 (-) 798 WP_085564083.1 ABC transporter ATP-binding protein -
  DBA17_RS09330 - 2227116..2227904 (+) 789 WP_128789445.1 hypothetical protein -
  DBA17_RS09335 - 2227974..2228213 (-) 240 WP_085564085.1 chaplin -
  DBA17_RS09340 vraR 2228385..2229026 (-) 642 WP_128789446.1 response regulator transcription factor Regulator
  DBA17_RS09345 - 2229019..2230164 (-) 1146 WP_128789447.1 GAF domain-containing sensor histidine kinase -
  DBA17_RS09350 - 2230421..2231116 (+) 696 WP_128789448.1 SDR family NAD(P)-dependent oxidoreductase -
  DBA17_RS09355 - 2231113..2232219 (+) 1107 WP_128789449.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  DBA17_RS09360 - 2232554..2233300 (+) 747 WP_128789450.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22977.31 Da        Isoelectric Point: 5.3758

>NTDB_id=245236 DBA17_RS09340 WP_128789446.1 2228385..2229026(-) (vraR) [Streptomyces sp. endophyte_N2]
MAEPIKVLLVDDHQVVRRGLRTFLEVQEDIVVVGEAADGAEGVARAEELRPDVVLMDVKMPGMDGIDALRRLRELDNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGQGRGSSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=245236 DBA17_RS09340 WP_128789446.1 2228385..2229026(-) (vraR) [Streptomyces sp. endophyte_N2]
GTGGCTGAGCCCATCAAGGTGCTGCTCGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGCACCTTCCTGGAGGTGCA
GGAGGACATAGTGGTCGTCGGCGAGGCGGCCGACGGCGCGGAAGGCGTGGCCCGCGCCGAGGAACTGCGGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCATCGACGCCCTGCGCAGGCTGCGTGAACTCGACAACCCCGCACGG
GTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTCGTACCGGCCCTGCGCGCGGGCGCCGCCGGGTATGTGTACAA
GGACGTGGACCCGGACGCCCTCGCCGGCGCGATCCGCTCCGTGCACGCCGGGCACATCCTGCTCCAGCCCGAGGTGGCGG
GCGCGCTGCTGTCCCAGGAGGAGGCCAACTCCGGTCAGGGCCGGGGGAGTTCCCTCACCGAGCGGGAGCGCGAGGTGCTC
GGGCTGATCGCCGACGGCCGCTCCAACCGGGAGATCGCCCGTGCGCTGGTGCTCTCCGAGAAGACGGTCAAGACACACGT
CTCCAACATCCTGATGAAGCTCGACCTCGCCGACCGCACCCAGGCCGCGCTGTGGGCCGTACGACACGGGGTTGCCGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(150-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7W3NLN3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.972

99.061

0.455
  degU Bacillus subtilis subsp. subtilis str. 168

37.557

100

0.39