Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   M28_RS02345 Genome accession   NC_007296
Coordinates   433002..433811 (+) Length   269 a.a.
NCBI ID   WP_002985641.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS6180     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 428002..438811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M28_RS02325 (M28_Spy0421) - 428444..429691 (+) 1248 WP_011284594.1 AMP-binding protein -
  M28_RS02330 (M28_Spy0422) - 429747..430781 (+) 1035 WP_011284595.1 DUF3114 domain-containing protein -
  M28_RS02335 (M28_Spy0423) vicR 430943..431653 (+) 711 WP_002985645.1 response regulator YycF Regulator
  M28_RS02340 (M28_Spy0424) vicK 431646..432998 (+) 1353 WP_002995609.1 cell wall metabolism sensor histidine kinase VicK Regulator
  M28_RS02345 (M28_Spy0425) vicX 433002..433811 (+) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  M28_RS02350 (M28_Spy0426) rnc 434244..434936 (+) 693 WP_011284596.1 ribonuclease III -
  M28_RS02355 (M28_Spy0427) smc 434937..438476 (+) 3540 WP_011284597.1 chromosome segregation protein SMC -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 30095.20 Da        Isoelectric Point: 5.5314

>NTDB_id=24482 M28_RS02345 WP_002985641.1 433002..433811(+) (vicX) [Streptococcus pyogenes MGAS6180]
MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLLAEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLD
IYANEKTWQLMDECNMLGKLDASQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKKIYLGHLSKENNIKELAHMTMVN
QLAMADLAVGTDFTVHDTSPDTACPLTDI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=24482 M28_RS02345 WP_002985641.1 433002..433811(+) (vicX) [Streptococcus pyogenes MGAS6180]
ATGAATGAGAGTGGTTTTAAATATAGTATTTTAGCATCTGGGTCCACAGGAAATTGTTTTTATTTAGAAACACCTAAAAA
ACGCTTATTGATTGATGCAGGGCTTACTGGTAAGAAAATTACCAGTCTTCTTGCTGAAATTGACCGCAAACCTGAGGATT
TGGATGCTATTTTGATTACCCATGAGCACTCTGACCATATTAAGGGTGTAGGCGTTATGGCCCGCAAATACCATTTGGAT
ATCTATGCTAATGAAAAAACATGGCAGCTGATGGATGAGTGCAATATGCTAGGTAAGCTTGATGCCTCACAAAAACATAT
TTTCCAAAGGGATAAAGTTTTGACCTTTGGAGATGTTGATATCGAAAGTTTTGGAGTCAGCCATGACGCTATTGATCCTC
AATTTTATCGGATTATGAAAGATAATAAGTCTTTTGTGATGTTGACAGATACAGGATATGTCAGTGATAGGATGACAGGT
ATTATTGAAAATGCAGATGGCTACTTGATTGAATCCAATCATGATATTGAAATTTTGAGATCAGGCTCTTATCCTTGGAG
CTTGAAGCAGCGTATTTTATCTGATTTAGGACATTTATCAAATGAAGATGGAGCGGGAGCCATGATTAGAAGCCTGGGGT
ACAATACCAAAAAAATATACCTAGGTCATCTGAGTAAAGAAAATAACATCAAAGAGTTAGCGCATATGACGATGGTCAAT
CAACTGGCTATGGCAGATTTAGCAGTAGGTACAGACTTTACGGTCCATGATACCTCTCCAGATACTGCTTGTCCATTAAC
TGATATTTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

75.836

100

0.758

Multiple sequence alignment