Detailed information NTG0024480

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SYC_RS02305
• Genome accession: NC_006576
• Coordinates: 500985..502142 (-)
• Length: 385 a.a.
• NCBI ID: WP_011242760.1
• Uniprot ID: Q31P88
• Organism: Synechococcus elongatus PCC 6301
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 495985..507142

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SYC_RS02280 (syc0443_d)	-	496655..497125 (+)	471	WP_011242755.1	CRR6 family NdhI maturation factor	-
SYC_RS02285 (syc0444_d)	apbC	497269..498354 (+)	1086	WP_011242756.1	iron-sulfur cluster carrier protein ApbC	-
SYC_RS02290 (syc0445_d)	rodA	498386..499651 (+)	1266	WP_011242757.1	rod shape-determining protein RodA	-
SYC_RS02295 (syc0446_d)	-	499749..500480 (+)	732	WP_011242758.1	glucosamine-6-phosphate deaminase	-
SYC_RS02300 (syc0447_c)	-	500545..500973 (-)	429	WP_011242759.1	hypothetical protein	-
SYC_RS02305 (syc0448_c)	htrA	500985..502142 (-)	1158	WP_011242760.1	HhoA/HhoB/HtrA family serine endopeptidase	Regulator
SYC_RS02310 (syc0449_d)	dnaA	502252..503700 (+)	1449	WP_011242761.1	chromosomal replication initiator protein DnaA	-
SYC_RS02315 (syc0450_d)	ubiE	503841..504542 (+)	702	WP_011242762.1	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	-
SYC_RS02320 (syc0451_d)	-	504545..505783 (+)	1239	WP_041676922.1	DUF445 domain-containing protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 40024.35 Da
• Isoelectric Point: 7.1776

>NTDB_id=24480 SYC_RS02305 WP_011242760.1 500985..502142(-) (htrA) [Synechococcus elongatus PCC 6301]
MTDSFFKRTLGLGSLVLLGLGGCSQVAQLPTPPNPLAVNRSEAASPNRPPLPLPENANFIVAAVERDGAAVVRINASRRV
SNGDPFGGLFGGPPAGGNRVERGSGSGFIFDSNGLLMTNAHVVEGADRVQVRLKDGRTYDGQVLGADPVTDVAVVKIDAK
DLPTVRIGNSDNLRPGEWAIAIGNPLGLDNTVTVGIISATGRSSSEVGIPDKRVGFIQTDAAINPGNSGGPLLNAAGEVI
GINTAIRADGQGIGFAVPINTARRIADQIIQTGKASHPLLGVQMLPLTPEIARENNRNPNASIDLPETDGALIVQVLPNS
PAAAAGIRRGDVITAAEGQPIRSASDLQTAVEKKKVGDRLALELLRQQQKRQVTVQLAEIPQQQG

Nucleotide

• Length: 1158 bp

>NTDB_id=24480 SYC_RS02305 WP_011242760.1 500985..502142(-) (htrA) [Synechococcus elongatus PCC 6301]
ATGACTGACAGCTTCTTCAAACGAACCTTGGGGCTCGGCAGCCTAGTGCTGCTGGGCTTAGGGGGCTGTTCACAGGTGGC
ACAGTTGCCTACGCCTCCCAATCCACTAGCGGTAAATCGCAGCGAAGCAGCATCACCCAATCGGCCCCCGTTACCCTTGC
CTGAAAACGCCAACTTCATTGTGGCGGCTGTCGAGCGGGATGGCGCTGCCGTGGTTCGGATCAATGCATCCCGCCGTGTC
AGCAATGGCGATCCCTTCGGCGGCTTGTTTGGCGGCCCGCCGGCGGGTGGCAATCGCGTCGAGCGGGGTTCCGGTTCTGG
CTTCATCTTTGATAGTAATGGTCTGCTGATGACCAATGCCCACGTTGTGGAAGGAGCCGATCGCGTTCAAGTGCGGCTCA
AAGACGGCCGAACCTACGATGGCCAAGTCCTAGGTGCTGACCCGGTTACGGATGTGGCCGTCGTCAAAATTGATGCCAAG
GATTTACCGACCGTCCGCATTGGCAATTCCGATAACCTCCGTCCTGGCGAATGGGCAATCGCGATCGGTAATCCCCTCGG
TCTCGACAACACCGTGACGGTGGGCATTATTAGCGCCACTGGGCGTTCGAGTTCAGAAGTTGGGATTCCCGACAAACGGG
TTGGCTTCATTCAGACCGATGCTGCGATCAACCCAGGCAACTCTGGCGGTCCCCTCTTGAATGCTGCTGGCGAAGTGATT
GGCATTAACACCGCGATTCGTGCCGACGGTCAGGGAATTGGCTTCGCGGTACCGATCAACACGGCCCGCCGCATTGCAGA
TCAAATTATTCAGACTGGCAAAGCCTCCCACCCGCTCTTGGGTGTTCAGATGCTGCCGCTGACCCCGGAAATTGCGCGCG
AGAATAACCGTAATCCCAACGCCAGCATTGATCTGCCGGAAACTGACGGTGCCTTAATTGTCCAAGTCTTGCCCAACTCT
CCAGCGGCGGCAGCCGGGATCCGTCGAGGGGACGTGATTACGGCGGCAGAAGGTCAGCCTATCCGCTCAGCTTCGGATCT
CCAGACAGCCGTGGAGAAGAAAAAGGTGGGCGATCGCTTGGCTCTGGAACTGCTCCGTCAGCAACAGAAGCGGCAGGTGA
CGGTTCAGCTGGCTGAAATTCCCCAGCAACAGGGCTAG

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (278-377)

• Peptidase family M50 (Peptidase_M50) (253-380)

• Trypsin-like peptidase domain (Trypsin_2) (105-242)

3D structure

• AlphaFold DB: Q31P88

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	34.889	100	0.369