Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   CK238_RS15565 Genome accession   NZ_CP023075
Coordinates   3079922..3080566 (-) Length   214 a.a.
NCBI ID   WP_014418762.1    Uniprot ID   A0A2Z4EIP2
Organism   Bacillus velezensis strain K26     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3074922..3085566
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CK238_RS15530 (CK238_15545) - 3076107..3076538 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  CK238_RS15535 (CK238_15550) - 3076538..3076879 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  CK238_RS15540 (CK238_15555) - 3076872..3078353 (+) 1482 WP_025650220.1 Na+/H+ antiporter subunit D -
  CK238_RS15545 (CK238_15560) - 3078359..3078835 (+) 477 WP_017419419.1 Na+/H+ antiporter subunit E -
  CK238_RS15550 (CK238_15565) - 3078835..3079119 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  CK238_RS15555 (CK238_15570) mnhG 3079103..3079477 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  CK238_RS15560 (CK238_15575) - 3079517..3079900 (-) 384 WP_017419422.1 hotdog fold thioesterase -
  CK238_RS15565 (CK238_15580) comA 3079922..3080566 (-) 645 WP_014418762.1 response regulator transcription factor Regulator
  CK238_RS15570 (CK238_15585) comP 3080647..3082950 (-) 2304 WP_063637045.1 histidine kinase Regulator
  CK238_RS15575 (CK238_15590) comX 3082970..3083149 (-) 180 WP_318010531.1 competence pheromone ComX -
  CK238_RS15580 (CK238_15595) comQ 3083103..3084089 (-) 987 WP_269321599.1 class 1 isoprenoid biosynthesis enzyme Regulator
  CK238_RS15585 (CK238_15600) degQ 3084220..3084360 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  CK238_RS15595 (CK238_15610) - 3084825..3085166 (+) 342 WP_014418765.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24302.70 Da        Isoelectric Point: 4.9953

>NTDB_id=244793 CK238_RS15565 WP_014418762.1 3079922..3080566(-) (comA) [Bacillus velezensis strain K26]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTQRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=244793 CK238_RS15565 WP_014418762.1 3079922..3080566(-) (comA) [Bacillus velezensis strain K26]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGTAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACACAGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z4EIP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

85.981

100

0.86

Multiple sequence alignment