Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   M28_RS01435 Genome accession   NC_007296
Coordinates   265569..266639 (+) Length   356 a.a.
NCBI ID   WP_010921893.1    Uniprot ID   A0A4U9C068
Organism   Streptococcus pyogenes MGAS6180     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 260569..271639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M28_RS01420 (M28_Spy0244) amiA 261097..263067 (+) 1971 WP_021340820.1 peptide ABC transporter substrate-binding protein Regulator
  M28_RS01425 (M28_Spy0245) amiC 263132..264634 (+) 1503 WP_002992227.1 ABC transporter permease Regulator
  M28_RS01430 (M28_Spy0246) amiD 264634..265560 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  M28_RS01435 (M28_Spy0247) amiE 265569..266639 (+) 1071 WP_010921893.1 ABC transporter ATP-binding protein Regulator
  M28_RS01440 (M28_Spy0248) amiF 266632..267555 (+) 924 WP_002986000.1 ATP-binding cassette domain-containing protein Regulator
  M28_RS10055 - 267593..267676 (-) 84 Protein_235 IS3 family transposase -
  M28_RS10060 - 267814..268129 (-) 316 Protein_236 IS3 family transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39703.77 Da        Isoelectric Point: 5.6707

>NTDB_id=24473 M28_RS01435 WP_010921893.1 265569..266639(+) (amiE) [Streptococcus pyogenes MGAS6180]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=24473 M28_RS01435 WP_010921893.1 265569..266639(+) (amiE) [Streptococcus pyogenes MGAS6180]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATTGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGGCACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9C068

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537

Multiple sequence alignment