Detailed information NTG0024418

Bioinformatically predicted

Overview

• Name: comK/comK1
• Type: Regulator
• Locus tag: SH_RS09370
• Genome accession: NC_007168
• Coordinates: 1973424..1974008 (+)
• Length: 194 a.a.
• NCBI ID: WP_011276196.1
• Uniprot ID: A0A2A1KAP4
• Organism: Staphylococcus haemolyticus JCSC1435
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1974537..1975853	1973424..1974008	flank	529

Gene organization within MGE regions

Location: 1973424..1975853

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SH_RS09370 (SH1926)	comK/comK1	1973424..1974008 (+)	585	WP_011276196.1	competence protein ComK	Regulator
SH_RS09385 (SH1927)	-	1974537..1975853 (+)	1317	WP_011276197.1	ISL3 family transposase	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 23002.43 Da
• Isoelectric Point: 9.2942

>NTDB_id=24418 SH_RS09370 WP_011276196.1 1973424..1974008(+) (comK/comK1) [Staphylococcus haemolyticus JCSC1435]
MTNISQSQNTVYIIRKGDMIIKPVIDDYEQTKGSEIWKYDSTIVSSPFKTQKIVERSCKFYGNSYISKKSETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENMWINMHYVHEIKPLKNRKCKIIFANHQTLTLNVSYHSIWHQYSNCIFYYYMVDKQ
SRMKSNNPEMPIDYEKTTLNIFEALSHYSLLQDK

Nucleotide

• Length: 585 bp

>NTDB_id=24418 SH_RS09370 WP_011276196.1 1973424..1974008(+) (comK/comK1) [Staphylococcus haemolyticus JCSC1435]
ATGACAAATATTTCTCAAAGCCAAAATACTGTATATATTATTCGAAAAGGAGATATGATAATCAAACCCGTCATTGATGA
TTATGAGCAAACAAAAGGATCAGAAATATGGAAATATGATTCCACAATAGTTTCAAGCCCATTCAAAACTCAAAAAATCG
TCGAACGCTCATGTAAATTTTATGGTAATAGCTATATTAGTAAGAAATCCGAAACACAACGAATTGCCGGCATTACTAGT
AAACCACCTATTTTATTGACTCCTCTCTTCCCCACTTATTTTTTCCCTACGCATTCAGACCGTTTAGAAGAAAACATGTG
GATTAATATGCATTATGTACATGAAATTAAACCTCTTAAAAATCGAAAATGTAAAATTATTTTTGCAAATCATCAAACAT
TAACACTTAATGTTTCCTACCACAGTATTTGGCACCAATACTCTAACTGCATTTTTTATTATTACATGGTCGATAAACAA
TCTCGTATGAAGTCAAACAATCCAGAAATGCCAATAGATTATGAGAAAACGACTTTAAATATTTTCGAAGCACTTTCACA
TTATTCACTATTACAAGATAAATAG

Domains

Predicted by InterproScan.

• ComK protein (ComK) (11-161)

3D structure

• AlphaFold DB: A0A2A1KAP4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comK/comK1	Staphylococcus aureus MW2	68.617	96.907	0.665
comK/comK1	Staphylococcus aureus N315	68.617	96.907	0.665