Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   STR_RS06680 Genome accession   NC_006449
Coordinates   1260538..1261182 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus CNRZ1066     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1255538..1266182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STR_RS06655 (str1417) - 1257639..1258637 (-) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -
  STR_RS06660 (str1418) trmD 1258639..1259358 (-) 720 WP_011227401.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  STR_RS06665 (str1419) rimM 1259348..1259866 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  STR_RS06680 (str1420) vraR 1260538..1261182 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  STR_RS06685 (str1421) - 1261172..1262182 (-) 1011 WP_011227402.1 sensor histidine kinase -
  STR_RS06690 (str1422) liaF 1262179..1262877 (-) 699 WP_011227403.1 cell wall-active antibiotics response protein LiaF -
  STR_RS11350 (str1423) - 1263143..1263298 (-) 156 WP_011226290.1 ion channel -
  STR_RS06695 (str1425) stkP/pknB 1263935..1265806 (-) 1872 WP_011226292.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=24371 STR_RS06680 WP_002951384.1 1260538..1261182(-) (vraR) [Streptococcus thermophilus CNRZ1066]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=24371 STR_RS06680 WP_002951384.1 1260538..1261182(-) (vraR) [Streptococcus thermophilus CNRZ1066]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACTGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment