Detailed information NTG0024297

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: STU_RS17095
• Genome accession: NC_006448
• Coordinates: 1460844..1461920 (-)
• Length: 358 a.a.
• NCBI ID: WP_011226464.1
• Uniprot ID: Q5M2Z4
• Organism: Streptococcus thermophilus LMG 18311
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1455844..1466920

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STU_RS17075 (stu1643)	-	1456956..1459022 (-)	2067	WP_011226460.1	cation:proton antiporter	-
STU_RS17080 (stu1644)	-	1459031..1459273 (-)	243	WP_011226461.1	hypothetical protein	-
STU_RS17085 (stu1645)	-	1459270..1459818 (-)	549	WP_011226462.1	tRNA (mnm(5)s(2)U34)-methyltransferase	-
STU_RS17090 (stu1646)	-	1459815..1460759 (-)	945	WP_011226463.1	TIGR01212 family radical SAM protein	-
STU_RS17095 (stu1647)	sepM	1460844..1461920 (-)	1077	WP_011226464.1	SepM family pheromone-processing serine protease	Regulator
STU_RS17100 (stu1648)	coaD	1461898..1462395 (-)	498	WP_011226465.1	pantetheine-phosphate adenylyltransferase	-
STU_RS17105 (stu1649)	rsmD	1462429..1463028 (-)	600	Protein_1438	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
STU_RS17110 (stu1650)	trxB	1463119..1464072 (-)	954	WP_255136104.1	thioredoxin-disulfide reductase	-
STU_RS17115 (stu1651)	-	1464105..1464329 (-)	225	WP_011226468.1	DUF4059 family protein	-
STU_RS17120 (stu1652)	amiE	1464544..1465287 (-)	744	WP_011226469.1	amino acid ABC transporter ATP-binding protein	Regulator
STU_RS17125 (stu1653)	-	1465287..1466033 (-)	747	WP_095559509.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39232.11 Da
• Isoelectric Point: 9.4944

>NTDB_id=24297 STU_RS17095 WP_011226464.1 1460844..1461920(-) (sepM) [Streptococcus thermophilus LMG 18311]
MANKTKSKSLLEKMWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVNKKADDSKGSYNFVAVAQTKAT
LALMLYTQFNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAVYQGLTLAGKEVSLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSTDMIKYVQGLKLGSKVKVTYMRDGKEKTATGKIIKIANGKNGIGIGLTDHTEIKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGAVGDIGGAYLKVKSAADSGADIFFVPNNLVTKEMKKADPD
AKTNYQEAKEAAEKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=24297 STU_RS17095 WP_011226464.1 1460844..1461920(-) (sepM) [Streptococcus thermophilus LMG 18311]
GTGGCAAACAAGACAAAATCTAAATCGCTATTAGAGAAAATGTGGCGTATTAAGTGGTGGTTATTAAGTATTTTTACGGT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCGCTCAATAATTACTATGTGGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACAGTGAATAAGAAAGCTGATGATTCTAAGGGCTCCTATAATTTTGTGGCGGTGGCTCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATACTCAGTTTAATGATTTTGCAAAGCTTCAAACGGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATGCGCATCAACCAATTTTACATGGAGACTTCTCAAAACCAAGCGGTTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGTTAGTTTGGAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCTGATACGGTGACGGCTGTTAATGGTAAGACCTTTGATAATTCTACTGACATGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAGGTCAAGGTCACTTATATGAGAGATGGCAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATTGCCA
ATGGCAAAAATGGTATTGGTATCGGCCTAACGGACCATACTGAGATCAAGAGTCCTGAGAATGTTAAGTTTAAACTGGAT
GGTGTCGGTGGGCCAAGTGCTGGTCTTATGTTTACCTTGGCTATTTACGATCAGGTGTCTGGTCAAGACCTCAAGGCTGG
CCGCAAGATTGCTGGTACAGGAACTATTGAAAAAGATGGGGCTGTCGGTGATATCGGTGGGGCCTATCTCAAGGTGAAAT
CTGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCTAGTAACTAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCTGAGAAACTGGGGACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATGA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (137-206)

3D structure

• AlphaFold DB: Q5M2Z4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	62.757	95.251	0.598