Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   CGP84_RS08240 Genome accession   NZ_CP022682
Coordinates   1648726..1649412 (-) Length   228 a.a.
NCBI ID   WP_072357801.1    Uniprot ID   A0A6B5EZE0
Organism   Staphylococcus aureus strain 78     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1643726..1654412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGP84_RS08220 (CGP84_01516) rpsT 1644640..1644891 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  CGP84_RS08225 (CGP84_01517) holA 1644936..1645910 (-) 975 WP_001282559.1 DNA polymerase III subunit delta -
  CGP84_RS08230 (CGP84_01518) comEC 1645967..1648168 (-) 2202 WP_042908045.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CGP84_RS08235 (CGP84_01519) - 1648173..1648634 (-) 462 WP_000439693.1 ComE operon protein 2 -
  CGP84_RS08240 (CGP84_01520) comEA 1648726..1649412 (-) 687 WP_072357801.1 ComEA family DNA-binding protein Machinery gene
  CGP84_RS08245 (CGP84_01521) - 1649452..1650168 (-) 717 WP_000084828.1 class I SAM-dependent methyltransferase -
  CGP84_RS08250 (CGP84_01522) rsfS 1650171..1650524 (-) 354 WP_001088020.1 ribosome silencing factor -
  CGP84_RS08255 (CGP84_01523) yqeK 1650525..1651109 (-) 585 WP_001019325.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  CGP84_RS08260 (CGP84_01524) nadD 1651099..1651668 (-) 570 WP_000725160.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  CGP84_RS08265 (CGP84_01525) yhbY 1651671..1651961 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  CGP84_RS08270 (CGP84_01526) aroE 1651965..1652771 (-) 807 WP_000666752.1 shikimate dehydrogenase -
  CGP84_RS08275 (CGP84_01527) yqeH 1652785..1653885 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25759.47 Da        Isoelectric Point: 9.6753

>NTDB_id=241619 CGP84_RS08240 WP_072357801.1 1648726..1649412(-) (comEA) [Staphylococcus aureus strain 78]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLSDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNINNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=241619 CGP84_RS08240 WP_072357801.1 1648726..1649412(-) (comEA) [Staphylococcus aureus strain 78]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTATCAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCACGTAAAAAAT
GGAAACATAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6B5EZE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

97.797

99.561

0.974
  comEA Staphylococcus aureus N315

97.797

99.561

0.974

Multiple sequence alignment