Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   SK637_RS08930 Genome accession   NZ_CP028415
Coordinates   1785953..1786393 (+) Length   146 a.a.
NCBI ID   WP_033689463.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1780953..1791393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS08900 (SK637_01736) - 1781106..1781369 (+) 264 WP_000166114.1 SemiSWEET family transporter -
  SK637_RS08905 (SK637_01737) - 1781522..1782553 (+) 1032 WP_033689458.1 S66 family peptidase -
  SK637_RS08910 (SK637_01738) - 1782615..1783178 (-) 564 WP_033689460.1 DNA-3-methyladenine glycosylase I -
  SK637_RS08915 (SK637_01739) ruvA 1783188..1783781 (-) 594 WP_033685590.1 Holliday junction branch migration protein RuvA Machinery gene
  SK637_RS08920 (SK637_01740) hexB 1783797..1785746 (-) 1950 WP_033689462.1 DNA mismatch repair endonuclease MutL Machinery gene
  SK637_RS08930 (SK637_01741) brsR 1785953..1786393 (+) 441 WP_033689463.1 LytTR family DNA-binding domain-containing protein Regulator
  SK637_RS08935 (SK637_01742) - 1786390..1786848 (+) 459 WP_033689465.1 DUF3021 domain-containing protein -
  SK637_RS08940 (SK637_01743) nrdI 1786896..1787360 (-) 465 WP_033689466.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  SK637_RS08945 (SK637_01744) - 1787438..1787971 (-) 534 WP_033689471.1 hypothetical protein -
  SK637_RS08950 (SK637_01745) - 1788032..1789318 (-) 1287 WP_033689473.1 response regulator transcription factor -
  SK637_RS08955 (SK637_01746) - 1789330..1791000 (-) 1671 WP_284698238.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17121.82 Da        Isoelectric Point: 8.2950

>NTDB_id=241277 SK637_RS08930 WP_033689463.1 1785953..1786393(+) (brsR) [Streptococcus mitis strain SK637]
MKVELQISETYKEEKLIVQAPQPTDKVQKVIEFAENLDQRETIKGKIDDQVYLVKIGKIQRFYIENRKVLAETASQTYNI
DLRLYQVLELLPSNFIQISQSEIININSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=241277 SK637_RS08930 WP_033689463.1 1785953..1786393(+) (brsR) [Streptococcus mitis strain SK637]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACAAGGAGGAAAAACTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTTGACCAAAGAGAAACAATCAAAGGAAAGATTGATGATCAGGTCTATCTCG
TTAAGATTGGTAAGATACAACGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACTGCGAGTCAGACCTACAACATT
GATTTGCGACTCTATCAAGTTCTTGAACTCTTGCCAAGCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCAA
CTCCATCTCTCATCTCAAGCTAACCCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTACCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363