Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SM12261_RS07660 Genome accession   NZ_CP028414
Coordinates   1511704..1512336 (-) Length   210 a.a.
NCBI ID   WP_000698442.1    Uniprot ID   -
Organism   Streptococcus mitis NCTC 12261     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1506704..1517336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM12261_RS07645 (SM12261_1478) recD/recD2/recDB 1507152..1509518 (+) 2367 WP_000454517.1 ATP-dependent RecD-like DNA helicase Machinery gene
  SM12261_RS07650 (SM12261_1479) tig 1509671..1510954 (-) 1284 WP_000116485.1 trigger factor -
  SM12261_RS07655 (SM12261_1480) - 1511038..1511703 (-) 666 WP_000050044.1 DNA alkylation repair protein -
  SM12261_RS07660 (SM12261_1481) vraR 1511704..1512336 (-) 633 WP_000698442.1 response regulator transcription factor Regulator
  SM12261_RS07665 (SM12261_1482) - 1512350..1513345 (-) 996 WP_000743694.1 sensor histidine kinase -
  SM12261_RS07670 (SM12261_1483) liaF 1513342..1514040 (-) 699 WP_001224652.1 cell wall-active antibiotics response protein LiaF -
  SM12261_RS07675 (SM12261_1484) fni 1514118..1515128 (-) 1011 WP_000210642.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  SM12261_RS07680 (SM12261_1485) - 1515112..1516119 (-) 1008 WP_000562409.1 phosphomevalonate kinase -
  SM12261_RS07685 (SM12261_1486) mvaD 1516106..1517059 (-) 954 WP_000373450.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23739.28 Da        Isoelectric Point: 4.9067

>NTDB_id=241156 SM12261_RS07660 WP_000698442.1 1511704..1512336(-) (vraR) [Streptococcus mitis NCTC 12261]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEATNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
SSYLDNEKIMPVLNAGARGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHIELHEDLTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVRHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=241156 SM12261_RS07660 WP_000698442.1 1511704..1512336(-) (vraR) [Streptococcus mitis NCTC 12261]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCTACCAACGGATCTCAAGGCATTGACTTAGCCTTGGAATTGCGTCCAGATGTCATTGTCATGGATA
TCGTTATGCCTGAGATGAATGGGATTGACGCGACCTTGGCTATCCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
AGCTCTTACTTAGACAATGAAAAAATCATGCCTGTCTTAAATGCTGGTGCTAGGGGATATATGCTCAAGACTTCTAGTGC
AGACGAACTACTCCATGCTGTTCGTAAGGTGGCTGCTGGCGAGTTGGCCATTGAGCAAGAGGTCAGCAAAAAAGTCGAAT
ACCACCGCAATCACATAGAACTACATGAGGACCTGACTGCGCGTGAGCGAGATGTTCTCCAACTTATCGCCAAGGGCTAC
GAAAATCAGCGTATAGCAGACGAACTTTTTATCTCTCTCAAGACGGTCAAGACCCATGTGTCTAATATCCTAGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCTGCAGTCTATGCCTTTCAGCACCACTTGGTGAGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.725

98.571

0.5
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414