Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   SM12261_RS07140 Genome accession   NZ_CP028414
Coordinates   1407610..1409457 (-) Length   615 a.a.
NCBI ID   WP_001061166.1    Uniprot ID   -
Organism   Streptococcus mitis NCTC 12261     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1402610..1414457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM12261_RS07110 (SM12261_1376) - 1403539..1403826 (-) 288 WP_000659133.1 rhodanese-like domain-containing protein -
  SM12261_RS07120 (SM12261_1377) - 1403941..1404519 (-) 579 WP_000078104.1 uracil-DNA glycosylase family protein -
  SM12261_RS07125 (SM12261_1378) pepV 1404573..1405973 (-) 1401 WP_000125031.1 dipeptidase PepV -
  SM12261_RS07130 (SM12261_1379) - 1405987..1406592 (-) 606 WP_000670177.1 nitroreductase family protein -
  SM12261_RS07135 (SM12261_1381) - 1406766..1407620 (-) 855 WP_000680852.1 metallophosphoesterase family protein -
  SM12261_RS07140 (SM12261_1382) uvrC 1407610..1409457 (-) 1848 WP_001061166.1 excinuclease ABC subunit UvrC Machinery gene
  SM12261_RS07145 (SM12261_1383) - 1409496..1410197 (-) 702 WP_001267186.1 M57 family metalloprotease -
  SM12261_RS07150 (SM12261_1384) - 1410276..1411508 (-) 1233 WP_001174044.1 aminoacyltransferase -
  SM12261_RS07155 (SM12261_1385) - 1411513..1412736 (-) 1224 WP_000286582.1 aminoacyltransferase -
  SM12261_RS07160 (SM12261_1386) - 1412870..1413649 (-) 780 WP_000290006.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 70638.14 Da        Isoelectric Point: 8.9828

>NTDB_id=241150 SM12261_RS07140 WP_001061166.1 1407610..1409457(-) (uvrC) [Streptococcus mitis NCTC 12261]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPYKVCF
YYHIGQCMAHTICKKDESYFKSMAQEVSDFLKGQDDKIIDDLKGKMATAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYYNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKVL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQRDGLTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMKHFKSL
TKIKEASVDEIVDVGVPRAVAEAVQRKLNPQEAVELAQVAEERVDYQTEGNHNET

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=241150 SM12261_RS07140 WP_001061166.1 1407610..1409457(-) (uvrC) [Streptococcus mitis NCTC 12261]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGTTACATTCACAAGGATAAAAACGGTAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAACCGCGTGCGGTCCTATTTTCGTGGAAGTCATGATACCAAGACGG
AAGCTCTGGTGTCTGAAATTGTAGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATTAAT
CTGATCAAGGAAAATAAGCCTAAATACAATATCATGCTCAAGGATGATAAGTCTTATCCTTTCATCAAAATCACTAATGA
GCGCTATCCTCGTTTAATTATCACCCGTCAGGTCAAGAAGGACGGCGGTCTCTACTTTGGACCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGGCTGCTGGATCGAATTTTCCCTTTTAGAAAGTGTACCAATCCACCGTATAAGGTCTGTTTT
TACTACCATATCGGCCAATGCATGGCCCACACTATCTGTAAGAAGGATGAGTCCTACTTCAAGTCTATGGCTCAGGAGGT
TTCTGATTTCCTAAAAGGGCAGGATGACAAAATCATTGATGACCTCAAGGGCAAAATGGCAACGGCAGCCCAGTCTATGG
AGTTTGAACGTGCGGCAGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAGAATCGTGATGTCTTTGGCTACTATGTGGACAAGGGTTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
AAAACTCATTGAACGTGACGTCAATCTATTCCCCTACTACAATGATCCGGATGAGGATTTTCTAACCTATGTAGGACAAT
TCTATCAAGAAAAATCTCATCTAGTTCCCAATGAGGTGCTGATTCCGCAGGATATTGACGAAGAAGCTGTCAAGGTCTTG
GTGGATACCAAGATTCTCAAACCCCAGCGTGGAGAGAAAAAGCAACTAGTCAATTTGGCTATAAAGAATGCTCGAGTCAG
TCTAGAGCAGAAGTTCAATTTGTTAGAAAAATCTGTCGAAAAGACCCAAGGAGCTATTGAAAATCTAGGTCGTTTGCTCC
AAATTCCCACCCCAGTTCGCATCGAGTCCTTCGATAACTCCAACATCATGGGAACTAGTCCTGTTTCAGCCATGGTGGTC
TTTGTCAACGGAAAACCTAGTAAGAAGGATTACCGTAAGTATAAAATCAAGACTGTCGTCGGGCCAGACGACTATGCTAG
TATGCGAGAGGTCATTCGCAGGCGCTATGGTCGAGTACAGCGTGACGGTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGACAAGGTCAAGTCAATATTGCCAAGCAAGTCATTCAAGAGGAGCTGGGCTTGGATATTCCCATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTTGAGGTGGTGGAGTTATCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGTATACAAGATGAGGTCCACCGCTTTGCTATAACTTTCCATCGCCAACTGCGCTCGAAAAATT
CTTTTTCATCACAACTGGATGGAATTGAAGGGCTGGGACCTAAACGCAAGCAGAATCTCATGAAGCATTTCAAGTCTCTA
ACAAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGATGTTGGAGTACCTAGAGCTGTTGCAGAGGCTGTGCAGAGGAA
GTTGAACCCGCAGGAAGCAGTGGAATTAGCTCAAGTGGCGGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATG
AAACATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

97.068

99.837

0.969
  uvrC Streptococcus pneumoniae R6

96.743

99.837

0.966
  uvrC Streptococcus pneumoniae D39

96.743

99.837

0.966