Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C6376_RS43120 Genome accession   NZ_CP028369
Coordinates   9743931..9744593 (-) Length   220 a.a.
NCBI ID   WP_107448614.1    Uniprot ID   -
Organism   Streptomyces sp. P3     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9738931..9749593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6376_RS43095 (C6376_43105) - 9739097..9740164 (+) 1068 WP_107448609.1 glycosyltransferase family 2 protein -
  C6376_RS44325 - 9740214..9740387 (+) 174 WP_159083466.1 hypothetical protein -
  C6376_RS43100 (C6376_43110) - 9740395..9741018 (+) 624 WP_107448610.1 class E sortase -
  C6376_RS46070 - 9741111..9741226 (-) 116 Protein_8496 gamma-glutamylcyclotransferase -
  C6376_RS43105 (C6376_43115) - 9741266..9742261 (-) 996 WP_159083467.1 hypothetical protein -
  C6376_RS43110 (C6376_43120) - 9742586..9742858 (+) 273 WP_107448612.1 DUF3253 domain-containing protein -
  C6376_RS43115 (C6376_43125) - 9743145..9743594 (-) 450 WP_107448613.1 spore-associated protein -
  C6376_RS43120 (C6376_43130) vraR 9743931..9744593 (-) 663 WP_107448614.1 response regulator transcription factor Regulator
  C6376_RS43125 (C6376_43135) - 9744590..9745717 (-) 1128 WP_107448615.1 sensor histidine kinase -
  C6376_RS43130 (C6376_43140) - 9745947..9746396 (+) 450 WP_254076309.1 DUF6223 family protein -
  C6376_RS43135 (C6376_43145) - 9746513..9747013 (-) 501 WP_254076310.1 GNAT family N-acetyltransferase -
  C6376_RS46075 - 9746961..9747116 (-) 156 WP_254076311.1 hypothetical protein -
  C6376_RS43140 (C6376_43150) - 9747512..9748138 (+) 627 WP_107448616.1 bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG -
  C6376_RS43145 (C6376_43155) - 9748148..9749185 (-) 1038 WP_254076312.1 Ig-like domain-containing protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23912.70 Da        Isoelectric Point: 4.9556

>NTDB_id=240887 C6376_RS43120 WP_107448614.1 9743931..9744593(-) (vraR) [Streptomyces sp. P3]
MIRVLLVDDQPLIRSGFRALLDLEDDIEVVAEAADGQEALALVRERLPDVALIDIQMPVMDGIEATRLIAADPTLAGVHV
VMLTNYGMDEYVFDALRAGAAGFLVKDILPEDFLHAVRVAARGDALLAPAITRKLIDRYVTQPPPARMGGRLEALTSRER
ESVALAAHGLSNDEIADRLVISPATAKTHINRAMVKLHVRDRAQLVVLAYESGLVTPHCS

Nucleotide


Download         Length: 663 bp        

>NTDB_id=240887 C6376_RS43120 WP_107448614.1 9743931..9744593(-) (vraR) [Streptomyces sp. P3]
GTGATCCGGGTCCTGCTGGTCGACGACCAGCCGCTCATCCGCAGCGGATTCCGCGCGCTGCTCGACCTCGAGGACGACAT
CGAGGTCGTGGCCGAGGCCGCCGACGGCCAGGAGGCCCTCGCGCTGGTCAGGGAGCGGCTGCCCGACGTCGCTCTCATCG
ACATCCAGATGCCCGTCATGGACGGCATCGAAGCGACCCGGCTCATCGCCGCGGACCCGACCCTGGCAGGCGTACACGTC
GTCATGCTGACCAACTACGGCATGGACGAGTACGTCTTCGACGCGTTGCGCGCCGGCGCCGCCGGCTTCCTGGTCAAGGA
CATCCTGCCGGAGGACTTCCTGCACGCCGTACGTGTCGCCGCCCGCGGCGACGCCCTGCTCGCGCCCGCCATCACCCGCA
AGCTCATCGACCGATACGTCACCCAGCCGCCGCCGGCCCGCATGGGCGGCAGGCTGGAAGCTCTGACCAGCCGCGAACGC
GAGTCGGTCGCCCTGGCCGCCCACGGTCTGTCCAACGACGAGATCGCCGACCGCCTGGTCATCAGCCCGGCGACCGCCAA
GACCCACATCAACCGGGCCATGGTCAAGCTCCACGTCCGCGACCGCGCCCAACTGGTGGTCCTCGCCTACGAATCCGGCC
TGGTTACTCCGCACTGCTCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.785

97.273

0.377
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.364