Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C6376_RS08295 Genome accession   NZ_CP028369
Coordinates   1859777..1860445 (-) Length   222 a.a.
NCBI ID   WP_107442825.1    Uniprot ID   -
Organism   Streptomyces sp. P3     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1854777..1865445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6376_RS08275 (C6376_08275) - 1855281..1856174 (+) 894 WP_107442822.1 ABC transporter ATP-binding protein -
  C6376_RS08280 (C6376_08280) - 1856171..1857766 (+) 1596 WP_107442823.1 ABC transporter permease -
  C6376_RS44690 - 1858016..1858291 (+) 276 WP_216825580.1 hypothetical protein -
  C6376_RS08290 (C6376_08290) - 1858274..1859491 (-) 1218 WP_107442824.1 cytochrome P450 -
  C6376_RS08295 (C6376_08295) vraR 1859777..1860445 (-) 669 WP_107442825.1 response regulator transcription factor Regulator
  C6376_RS08300 (C6376_08300) - 1860442..1861830 (-) 1389 WP_107442826.1 sensor histidine kinase -
  C6376_RS08305 (C6376_08305) - 1862020..1862901 (-) 882 WP_107442827.1 alpha/beta hydrolase -
  C6376_RS08310 (C6376_08310) kynU 1863205..1864389 (-) 1185 WP_107442828.1 kynureninase -
  C6376_RS08315 (C6376_08315) - 1864382..1865227 (-) 846 WP_107442829.1 tryptophan 2,3-dioxygenase family protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23954.61 Da        Isoelectric Point: 4.9749

>NTDB_id=240841 C6376_RS08295 WP_107442825.1 1859777..1860445(-) (vraR) [Streptomyces sp. P3]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVHRVRELAPDVVLMDIRMPELNGIEATREIVAAGGTSKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPSVTRRLITEFSKLSDTPGSVRAAVHASYGDLT
ERETEVLVLIAQGLSNSEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=240841 C6376_RS08295 WP_107442825.1 1859777..1860445(-) (vraR) [Streptomyces sp. P3]
ATGACGATCCGGGTTCTGATCGCCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCGGA
CATCGAGGTGGTGGGCGAGGCGGTGAACGGCCGGGAGGCGGTGCACCGGGTCCGCGAGCTGGCGCCCGACGTGGTCCTGA
TGGACATCCGCATGCCGGAGCTGAACGGCATCGAGGCGACGCGGGAGATCGTCGCGGCGGGCGGCACGTCGAAGGTCCTG
GTCCTGACCACCTTCGACCTCGACGAGTACGTCTACCAGGCGCTGCGCGCGGGAGCCTCCGGCTTCCTCCTGAAGGACGC
CTCGGCCCGCCAGCTGGCGGACGGGGTGCGGGTGGTGGCGGCCGGCGAGGCGCTTCTCGCCCCGTCCGTCACCCGGCGTC
TGATCACGGAGTTCTCCAAGCTCTCGGACACCCCCGGGTCGGTCCGCGCGGCCGTCCATGCGTCCTACGGCGACCTGACC
GAACGGGAGACGGAGGTGCTGGTCCTCATCGCCCAGGGCCTGTCGAACTCGGAGATCGCCGAGCGGCTGGTGGTGGCGGA
GTCGACCATCAAGACGCACGTGAGCAGGATCCTGGTGAAGCTGGGCCTGCGGGACCGCACCCAGGCGGCGGTGTTCGCGT
ACGAGGCGAGGCTGGTGACGCCGGGCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-213)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.749

98.649

0.441
  degU Bacillus subtilis subsp. subtilis str. 168

43.578

98.198

0.428