Detailed information NTG0240791

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: C7Y67_RS13320
• Genome accession: NZ_CP028342
• Coordinates: 2675051..2677624 (-)
• Length: 857 a.a.
• NCBI ID: WP_005460310.1
• Uniprot ID: Q87S63
• Organism: Vibrio parahaemolyticus isolate R13
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2670051..2682624

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7Y67_RS13320 (C7Y67_13315)	clpC	2675051..2677624 (-)	2574	WP_005460310.1	ATP-dependent chaperone ClpB	Regulator
C7Y67_RS13325 (C7Y67_13320)	pgeF	2677772..2678500 (-)	729	WP_057619181.1	peptidoglycan editing factor PgeF	-
C7Y67_RS13330 (C7Y67_13325)	rluD	2678502..2679479 (-)	978	WP_005460300.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
C7Y67_RS13335 (C7Y67_13330)	comL	2679616..2680344 (+)	729	WP_005460312.1	outer membrane protein assembly factor BamD	Machinery gene
C7Y67_RS13340 (C7Y67_13335)	-	2680479..2681960 (+)	1482	WP_025547674.1	lytic transglycosylase F	-
C7Y67_RS13345 (C7Y67_13340)	raiA	2682291..2682617 (+)	327	WP_005468590.1	ribosome-associated translation inhibitor RaiA	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95872.46 Da
• Isoelectric Point: 5.1096

>NTDB_id=240791 C7Y67_RS13320 WP_005460310.1 2675051..2677624(-) (clpC) [Vibrio parahaemolyticus isolate R13]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLDVDVTHLRSKLGEMLDRLPKVSGIGGD
VQLSSSMGTLFNLCDKVAQKRQDSYISSEVFLLAALEDRGPLGQLLKEVGLTEQKVSQAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIVNNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNVILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTVAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRLQIDSKPESLDKLERKIIQLKIEQQALSNEHDEASEKRLQALNDELNEKEREYAELEEVWNTEKAALSGTQHIKSELE
QARMDMEFARRAGDLNRMSELQYGRIPELEKQLDLATQAEMQEMTLLRNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEDVLHNRVVGQSEAVAVVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLASFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFATLDYQGIKSEVMDVVSKHFRPEFLNRVDEIVVFHPLGQEHIKSIASIQLERLAKRLEEKGYQLEVSDKAL
DLIAQVGFDPVYGARPLKRAIQQNVENPLAKSILAGEIVPDKKVQLIVTNDQILAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=240791 C7Y67_RS13320 WP_005460310.1 2675051..2677624(-) (clpC) [Vibrio parahaemolyticus isolate R13]
ATGCGTCTTGATAGATTTACCAGTAAGTTTCAAATCGCTATCTCTGATGCTCAATCACTAGCGTTAGGGCGCGATCATCA
GTACATCGAGCCAGTTCACTTAATGGTGGCTTTGCTTGATCAAAATGGCAGTCCAATTCGTCCATTGCTGACAATGCTGG
ACGTGGATGTAACTCATCTCCGCTCAAAGCTGGGCGAAATGCTTGATCGATTACCAAAGGTGAGTGGCATCGGTGGTGAT
GTGCAGCTTTCTAGCTCGATGGGGACTTTGTTCAATCTGTGTGACAAAGTGGCTCAAAAGCGTCAAGACTCCTACATCTC
GTCCGAAGTCTTCTTGCTTGCGGCATTAGAAGATCGCGGTCCTTTAGGGCAACTACTTAAAGAAGTGGGGCTCACCGAGC
AAAAAGTGAGTCAAGCGATTGAAAAGATCAGAGGTGGTCAAAAGGTCAATGATCCAAATGCTGAAGAGCTACGTCAGGCT
CTTGAAAAATTCACCATCGATTTAACTGAGCGAGCTGAGCAAGGCAAATTGGATCCTGTAATTGGTCGAGATGATGAAAT
TCGTCGCACGATTCAAGTATTGCAACGTCGCACCAAAAACAACCCAGTGATCATCGGTGAGCCTGGTGTGGGTAAAACCG
CAATTGTGGAAGGCTTGGCGCAGCGAATTGTTAATAACGAAGTGCCAGAAGGTCTACGCGGTCGCCGTGTTCTATCACTG
GATATGGGCGCACTTGTTGCTGGCGCAAAATACCGTGGTGAATTTGAAGAGCGTTTAAAATCAGTATTGAATGAACTTGC
TAAAGAAGAAGGCAACGTCATCCTCTTCATTGATGAACTACACACTATGGTCGGCGCTGGTAAAGGTGAAGGCTCAATGG
ATGCGGGCAACATGCTCAAACCAGCATTGGCTCGCGGCGAACTTCACTGTGTTGGTGCAACAACATTGGATGAGTACCGT
CAATACATCGAAAAGGATGCTGCATTAGAACGTCGTTTCCAAAAAGTGCTGGTGGATGAGCCGACAGTAGAAGATACGGT
GGCTATTCTTCGTGGTCTGAAAGAGCGTTATGAACTTCATCACCATGTAGAAATTACTGACCCAGCGATTGTTGCAGCGG
CAAGTTTGTCGCACCGTTATATTTCGGACCGTCAGTTGCCAGATAAAGCCATTGACTTGATCGATGAAGCGGCTTCAAGC
ATTCGTCTACAAATCGATTCAAAACCAGAATCATTGGATAAGCTTGAGCGTAAAATCATCCAACTAAAAATTGAGCAACA
AGCACTAAGTAACGAGCACGATGAAGCGAGTGAAAAGCGTCTGCAAGCATTGAATGATGAGTTGAATGAGAAAGAACGCG
AATACGCAGAGTTAGAAGAGGTTTGGAATACAGAAAAAGCCGCACTTTCTGGTACTCAGCATATTAAATCTGAACTAGAG
CAAGCTCGCATGGACATGGAGTTTGCGCGTCGTGCTGGTGATCTGAACCGAATGTCTGAGCTTCAATACGGCCGTATTCC
GGAATTAGAGAAGCAACTAGACTTGGCGACTCAGGCTGAAATGCAAGAAATGACGCTGCTTCGCAATAAGGTAACAGATA
ACGAAATCGCAGAAGTGCTTTCTAAACAAACCGGCATTCCAGTATCTAAGATGCTAGAAGCGGAGAAAGAGAAACTACTT
CGCATGGAAGATGTGCTTCACAATCGTGTTGTAGGGCAAAGCGAAGCAGTTGCAGTGGTATCGAACGCGATTCGTCGTAG
CCGAGCTGGGCTTTCTGATCCAAACCGACCAATTGGTTCCTTCTTATTCTTAGGCCCAACTGGTGTCGGTAAAACGGAAT
TATGTAAGACACTCGCGAGCTTCATGTTCGACAGTGAAGATGCAATGGTACGTATCGACATGTCGGAGTTCATGGAGAAA
CACTCAGTGGCAAGATTAGTGGGTGCGCCTCCAGGTTACGTTGGTTACGAAGAGGGTGGTTATCTAACTGAAGCGGTTCG
TCGTAAACCATACTCAGTGATCTTGTTGGATGAAGTAGAAAAAGCACATCCAGATGTGTTCAATATTCTTCTGCAGGTGC
TTGATGATGGCCGACTCACTGATGGACAAGGTCGTACGGTTGATTTTCGTAACACCGTCGTGATCATGACATCAAACTTG
GGTTCCTCTCGAATCCAAGAGAACTTCGCCACATTGGACTATCAAGGTATCAAGAGTGAAGTGATGGATGTGGTTAGCAA
ACACTTCCGCCCAGAGTTCTTGAACCGTGTTGACGAAATAGTGGTATTCCACCCACTTGGTCAAGAGCACATTAAGTCCA
TTGCTTCTATTCAATTAGAACGCTTGGCAAAACGACTAGAAGAAAAAGGGTATCAATTAGAGGTTTCTGATAAAGCACTC
GACTTGATCGCCCAAGTCGGTTTCGACCCAGTATACGGTGCACGTCCTTTAAAACGTGCAATTCAACAGAATGTCGAGAA
CCCATTAGCTAAATCCATTCTTGCTGGTGAAATAGTTCCAGACAAGAAAGTGCAGCTAATCGTTACTAATGACCAAATTC
TCGCTCATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-760)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-320)

3D structure

• AlphaFold DB: Q87S63

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.597	100	0.471
clpE	Streptococcus mutans UA159	49.115	79.113	0.389
clpE	Streptococcus pneumoniae Rx1	47.701	81.214	0.387
clpE	Streptococcus pneumoniae D39	47.701	81.214	0.387
clpE	Streptococcus pneumoniae R6	47.701	81.214	0.387
clpC	Lactococcus lactis subsp. cremoris KW2	46.965	80.747	0.379