Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   GK_RS12535 Genome accession   NC_006510
Coordinates   2460963..2461259 (-) Length   98 a.a.
NCBI ID   WP_011231915.1    Uniprot ID   U2X350
Organism   Geobacillus kaustophilus HTA426     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2455963..2466259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GK_RS12500 (GK2426) - 2456564..2458228 (+) 1665 WP_011231908.1 DEAD/DEAH box helicase -
  GK_RS12505 (GK2427) - 2458215..2459009 (+) 795 WP_011231909.1 YqhG family protein -
  GK_RS12510 (GK2428) - 2459112..2459291 (-) 180 WP_011231910.1 YqzE family protein -
  GK_RS12515 (GK2429) comGG 2459337..2459726 (-) 390 WP_011231911.1 competence type IV pilus minor pilin ComGG -
  GK_RS12520 (GK2430) comGF 2459801..2460247 (-) 447 WP_021322351.1 competence type IV pilus minor pilin ComGF -
  GK_RS12525 (GK2431) - 2460226..2460552 (-) 327 WP_011231913.1 type II secretion system protein -
  GK_RS12530 (GK2432) comGD 2460536..2460973 (-) 438 WP_011231914.1 competence type IV pilus minor pilin ComGD -
  GK_RS12535 (GK2433) comGC 2460963..2461259 (-) 297 WP_011231915.1 competence type IV pilus major pilin ComGC Machinery gene
  GK_RS12540 (GK2434) comGB 2461462..2462490 (-) 1029 WP_041467897.1 competence type IV pilus assembly protein ComGB -
  GK_RS12545 (GK2435) comGA 2462487..2463560 (-) 1074 WP_011231917.1 competence type IV pilus ATPase ComGA Machinery gene
  GK_RS12550 (GK2436) - 2463753..2464451 (+) 699 WP_011231918.1 helix-turn-helix transcriptional regulator -
  GK_RS12555 (GK2437) - 2464610..2464852 (+) 243 WP_008879854.1 DUF2626 family protein -
  GK_RS12560 (GK2438) - 2464936..2466069 (-) 1134 WP_020278526.1 class I SAM-dependent methyltransferase -

Sequence


Protein


Download         Length: 98 a.a.        Molecular weight: 10749.59 Da        Isoelectric Point: 7.2422

>NTDB_id=24045 GK_RS12535 WP_011231915.1 2460963..2461259(-) (comGC) [Geobacillus kaustophilus HTA426]
MNQKGFTLIEMLIVMMVISVLLLIAIPNMTKHNSMINSKGCEAFLNTVQAQVKAYEMEHNKIPTVQELLAGRYIKSDKCP
NGHAIQISANGDVSESGS

Nucleotide


Download         Length: 297 bp        

>NTDB_id=24045 GK_RS12535 WP_011231915.1 2460963..2461259(-) (comGC) [Geobacillus kaustophilus HTA426]
ATGAATCAAAAGGGATTCACATTGATCGAAATGTTGATCGTTATGATGGTGATTTCTGTCCTGCTGCTGATTGCCATTCC
GAATATGACAAAGCACAACAGCATGATCAATTCGAAAGGATGCGAGGCGTTTTTGAACACCGTGCAAGCGCAGGTGAAAG
CGTATGAGATGGAGCATAACAAAATTCCGACGGTGCAGGAATTGCTCGCTGGCCGCTATATCAAGTCGGACAAATGTCCG
AACGGTCATGCCATCCAAATCAGCGCGAACGGCGATGTGAGTGAAAGTGGCTCGTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB U2X350

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Bacillus subtilis subsp. subtilis str. 168

52.747

92.857

0.49

  comGC Staphylococcus aureus MW2

41.935

94.898

0.398

  comGC Staphylococcus aureus N315

41.935

94.898

0.398


Multiple sequence alignment