Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C7M28_RS16925 Genome accession   NZ_CP028215
Coordinates   3248836..3249480 (+) Length   214 a.a.
NCBI ID   WP_003245647.1    Uniprot ID   O07528
Organism   Bacillus subtilis strain SRCM102750     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3243836..3254480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M28_RS16910 (C7M28_03325) glpD 3244007..3245674 (+) 1668 WP_003233382.1 glycerol-3-phosphate dehydrogenase -
  C7M28_RS16915 (C7M28_03326) pgcA 3245806..3247551 (+) 1746 WP_003244986.1 phosphoglucomutase -
  C7M28_RS16920 (C7M28_03327) yhcY 3247700..3248839 (+) 1140 WP_003245750.1 two-component system sensor histidine kinase YhcY -
  C7M28_RS16925 (C7M28_03328) vraR 3248836..3249480 (+) 645 WP_003245647.1 two-component system response regulator YhcZ Regulator
  C7M28_RS16930 (C7M28_03329) yhdA 3249477..3250001 (+) 525 WP_003244703.1 FMN-dependent NADPH-azoreductase -
  C7M28_RS16935 (C7M28_03330) yhdB 3250016..3250258 (-) 243 WP_003233373.1 YhdB family protein -
  C7M28_RS16940 (C7M28_03331) yhdC 3250459..3250782 (+) 324 WP_003233371.1 YqzG/YhdC family protein -
  C7M28_RS16945 (C7M28_03332) lytF 3250824..3252290 (-) 1467 WP_015252477.1 peptidoglycan endopeptidase LytF -
  C7M28_RS16950 (C7M28_03333) nsrR 3252442..3252882 (-) 441 WP_014479293.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24022.59 Da        Isoelectric Point: 6.3034

>NTDB_id=240246 C7M28_RS16925 WP_003245647.1 3248836..3249480(+) (vraR) [Bacillus subtilis strain SRCM102750]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=240246 C7M28_RS16925 WP_003245647.1 3248836..3249480(+) (vraR) [Bacillus subtilis strain SRCM102750]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O07528

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.411