Detailed information NTG0023997

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: TTH_RS00640
• Genome accession: NC_006461
• Coordinates: 121447..122451 (+)
• Length: 334 a.a.
• NCBI ID: WP_011227724.1
• Uniprot ID: -
• Organism: Thermus thermophilus HB8
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 116447..127451

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TTH_RS00610 (TTHA0116)	-	116598..117818 (+)	1221	WP_011227721.1	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-
TTH_RS00615 (TTHA0117)	-	117828..118376 (+)	549	WP_011227722.1	Uma2 family endonuclease	-
TTH_RS00620 (TTHA0118)	-	118354..119328 (-)	975	WP_011227723.1	bifunctional oligoribonuclease/PAP phosphatase NrnA	-
TTH_RS00630 (TTHA0119)	-	119525..120412 (-)	888	WP_011174227.1	acyltransferase	-
TTH_RS00635 (TTHA0120)	era	120457..121362 (-)	906	WP_008630929.1	GTPase Era	-
TTH_RS00640 (TTHA0121)	dprA	121447..122451 (+)	1005	WP_011227724.1	DNA-processing protein DprA	Machinery gene
TTH_RS00645 (TTHA0122)	-	122455..123363 (-)	909	WP_011227725.1	manganese catalase family protein	-
TTH_RS00650 (TTHA0123)	-	123473..124426 (+)	954	WP_011227726.1	hydrogen peroxide-inducible genes activator	-
TTH_RS00655 (TTHA0124)	-	124413..125369 (+)	957	WP_164926019.1	branched-chain amino acid transaminase	-
TTH_RS00660 (TTHA0125)	-	125359..125547 (+)	189	WP_011174222.1	hypothetical protein	-
TTH_RS00665 (TTHA0126)	-	125549..125788 (+)	240	WP_008630920.1	hypothetical protein	-
TTH_RS00670 (TTHA0127)	trmH	125778..126362 (-)	585	WP_011174221.1	tRNA (guanosine(18)-2'-O)-methyltransferase TrmH	-
TTH_RS00675 (TTHA0128)	hisG	126359..126979 (-)	621	WP_011174220.1	ATP phosphoribosyltransferase	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 36145.98 Da
• Isoelectric Point: 6.5207

>NTDB_id=23997 TTH_RS00640 WP_011227724.1 121447..122451(+) (dprA) [Thermus thermophilus HB8]
MDPLALALLPGIGPKRLLEVLKAEDPLGFLRERFPEAWRHLPEAEAQAERERGRAEALGVRLLGLWEEGFPEGLRALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARRLARELAEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLCRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPTDER
SLGANRLIQDGAYPVLSAEDVLSYLGMSARPKPLPGLSPEEEALYALLQEKKEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide

• Length: 1005 bp

>NTDB_id=23997 TTH_RS00640 WP_011227724.1 121447..122451(+) (dprA) [Thermus thermophilus HB8]
GTGGACCCCTTGGCCCTCGCCCTCCTCCCGGGCATCGGCCCCAAGCGGCTTTTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCGGCACCTCCCCGAGGCCGAGGCCCAGGCGGAAAGGGAAAGGGGGC
GCGCCGAGGCCCTAGGGGTGCGCCTCCTGGGCCTCTGGGAGGAGGGCTTCCCCGAGGGGCTGAGGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCCCC
TTGGGCCCTGGCCTTTGCCAGGAGGCTCGCCCGGGAGCTGGCCGAGGCCGGGCTTTGGGTGGTCTCGGGCCTCGCCCGGG
GCATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCTTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGGACCGGCCCTAAGCC
CGAGTTCTTTCCCCGGCGAAACCGCCTCATCGCCGGGCTTTGCCGGGCAGTGGTCGTGGTGGAGGCCCCCCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCCTGGAGCTCGGCAAGGAGGTGCTGGCCGTGCCCGGAAGGCCCACGGACGAGCGC
TCCCTGGGGGCGAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGACGTCCTCTCCTACCTGGGAAT
GTCCGCAAGGCCCAAGCCCCTCCCGGGCCTCTCCCCGGAGGAGGAAGCCCTTTACGCCCTCCTGCAGGAAAAGAAGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTCCTCACCCTCTTGGAGCTAAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (269-329)

• DNA recombination-mediator protein A (DNA_processg_A) (56-255)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Thermus thermophilus HB27	98.503	100	0.985
dprA	Vibrio campbellii strain DS40M4	38.268	100	0.41
dprA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	45.89	87.425	0.401
dprA	Vibrio cholerae strain A1552	37.255	100	0.398