Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C7M26_RS18735 Genome accession   NZ_CP028212
Coordinates   3579626..3580261 (+) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain SRCM102748     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3574626..3585261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M26_RS18710 (C7M26_03689) liaI 3575753..3576133 (+) 381 WP_003228504.1 cell envelope stress-induced membrane anchor protein LiaI -
  C7M26_RS18715 (C7M26_03690) liaH 3576160..3576837 (+) 678 WP_032722497.1 stress responsive protein LiaH -
  C7M26_RS18720 (C7M26_03691) liaG 3576938..3577810 (+) 873 WP_015714683.1 DUF4097 domain-containing protein -
  C7M26_RS18725 (C7M26_03692) liaF 3577844..3578569 (+) 726 WP_015714682.1 LiaRS two-component regulatory system accessory protein LiaF -
  C7M26_RS18730 (C7M26_03693) liaS 3578566..3579648 (+) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  C7M26_RS18735 (C7M26_03694) vraR 3579626..3580261 (+) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  C7M26_RS18740 (C7M26_03695) gerAC 3580269..3581390 (-) 1122 WP_003243203.1 spore germination receptor protein GerAC -
  C7M26_RS18745 (C7M26_03696) gerAB 3581387..3582484 (-) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  C7M26_RS18750 (C7M26_03697) gerAA 3582453..3583901 (-) 1449 WP_003243555.1 spore germination receptor protein GerAA -
  C7M26_RS18755 (C7M26_03698) yvzF 3584019..3584204 (+) 186 WP_003228521.1 YvzF family protein -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=239964 C7M26_RS18735 WP_003243201.1 3579626..3580261(+) (vraR) [Bacillus subtilis strain SRCM102748]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=239964 C7M26_RS18735 WP_003243201.1 3579626..3580261(+) (vraR) [Bacillus subtilis strain SRCM102748]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408

Multiple sequence alignment