Detailed information NTG0023951

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: STR_RS01510
• Genome accession: NC_006449
• Coordinates: 270119..271018 (+)
• Length: 299 a.a.
• NCBI ID: WP_011226854.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus CNRZ1066
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 265119..276018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR_RS01490 (str0265)	trkA	266255..267604 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
STR_RS01495 (str0267)	-	267863..268402 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
STR_RS01500 (str0268)	-	268714..269271 (+)	558	WP_002949523.1	ECF transporter S component	-
STR_RS01505 (str0269)	-	269274..269924 (+)	651	WP_011226853.1	phosphatase PAP2 family protein	-
STR_RS01510 (str0270)	comR	270119..271018 (+)	900	WP_011226854.1	helix-turn-helix domain-containing protein	Regulator
STR_RS11065	-	271257..272435 (+)	1179	Protein_245	ABC transporter transmembrane domain-containing protein	-
STR_RS01535 (str0275)	-	272721..273289 (+)	569	Protein_246	ATP-binding cassette domain-containing protein	-
STR_RS01540 (str0276)	-	273397..273708 (+)	312	WP_011226857.1	DUF805 domain-containing protein	-
STR_RS11070 (str0277)	-	273676..273960 (-)	285	WP_231108755.1	hypothetical protein	-
STR_RS11075 (str0278)	-	274200..274502 (-)	303	WP_011226859.1	hypothetical protein	-
STR_RS11080 (str0279)	-	274726..275097 (-)	372	WP_231108754.1	hypothetical protein	-
STR_RS01550 (str0280)	-	275502..276017 (+)	516	WP_011226861.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35317.79 Da
• Isoelectric Point: 5.1073

>NTDB_id=23951 STR_RS01510 WP_011226854.1 270119..271018(+) (comR) [Streptococcus thermophilus CNRZ1066]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=23951 STR_RS01510 WP_011226854.1 270119..271018(+) (comR) [Streptococcus thermophilus CNRZ1066]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421