Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   CGZ53_RS06975 Genome accession   NZ_CP022435
Coordinates   1373196..1374497 (-) Length   433 a.a.
NCBI ID   WP_100912182.1    Uniprot ID   -
Organism   Streptococcus uberis strain NZ01     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1368196..1379497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGZ53_RS06965 (CGZ53_06960) hpf 1371908..1372456 (-) 549 WP_015911695.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  CGZ53_RS06970 (CGZ53_06965) - 1372532..1373206 (-) 675 WP_015911696.1 ComF family protein -
  CGZ53_RS06975 (CGZ53_06970) comFA/cflA 1373196..1374497 (-) 1302 WP_100912182.1 DEAD/DEAH box helicase Machinery gene
  CGZ53_RS06980 (CGZ53_06975) - 1374554..1375183 (+) 630 WP_015911698.1 YigZ family protein -
  CGZ53_RS06985 (CGZ53_06980) cysK 1375292..1376224 (+) 933 WP_100912183.1 cysteine synthase A -
  CGZ53_RS06990 (CGZ53_06985) - 1376239..1376595 (-) 357 WP_015911700.1 S1 RNA-binding domain-containing protein -
  CGZ53_RS06995 (CGZ53_06990) - 1376595..1377995 (-) 1401 WP_037593423.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  CGZ53_RS07000 (CGZ53_06995) - 1378029..1378670 (-) 642 WP_046390058.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 50111.46 Da        Isoelectric Point: 10.1493

>NTDB_id=239391 CGZ53_RS06975 WP_100912182.1 1373196..1374497(-) (comFA/cflA) [Streptococcus uberis strain NZ01]
MDELNAYDGRRFTPYQVPKQLLQYASVQDSMYKEGSKWFCGRCHMPVSNKNKLPNGHYYCRECIIFGRNESHSHLYTFPA
RPFPKTQALKWMGQLTPFQEKISRQLVSESKKKQKRLVHAVTGAGKTEMIYGLITSYLNEGKWVCIASPRIDVCIELYGR
LKNDFTCPITLMHGESEVYHKSPLIVATTHQLLKFYRAFDLMVIDEVDSFPFVGNSILSRAVTSALKEEGEILYLTATST
KELDLKVKRGDIEKLTLPRRFHNQPLIVPKFKLILNLEESLQKKRLPIPLLNMIRRQRKTNYQLLIFHPIIDKGEEFFRL
LATKLRNEKIAYVSSQSDHRKQIIEQFRKSEISILITTTILERGVTFPGVDVFVLLSHHKLFNASSLIQISGRVGRSLDR
PTGQLFFLHQGISIDMLKAKKEIIRMNREAYGQ

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=239391 CGZ53_RS06975 WP_100912182.1 1373196..1374497(-) (comFA/cflA) [Streptococcus uberis strain NZ01]
ATGGATGAATTAAATGCTTACGATGGCCGTCGCTTCACTCCTTACCAAGTTCCAAAACAGTTATTGCAGTATGCAAGTGT
TCAAGATAGTATGTACAAAGAGGGTTCTAAGTGGTTTTGTGGCAGATGTCATATGCCTGTTTCAAATAAAAACAAGTTAC
CTAATGGTCACTACTATTGTAGGGAATGTATTATTTTCGGTCGAAATGAGAGTCATTCTCACCTTTATACTTTTCCGGCT
AGGCCATTTCCTAAGACTCAGGCTCTAAAGTGGATGGGACAATTAACACCATTTCAAGAAAAAATATCGCGTCAGCTTGT
CTCAGAATCAAAGAAAAAACAAAAGCGACTGGTGCATGCTGTTACTGGTGCAGGCAAAACGGAGATGATTTATGGATTAA
TAACCTCTTATCTTAATGAAGGAAAATGGGTTTGTATAGCTAGTCCGCGTATTGATGTTTGTATTGAACTGTACGGTCGC
TTAAAAAATGATTTTACCTGTCCAATTACGCTGATGCATGGAGAATCAGAAGTCTATCACAAAAGTCCCTTAATCGTTGC
TACGACGCATCAGTTGTTAAAGTTTTATCGGGCCTTTGATTTAATGGTTATTGATGAAGTTGATTCATTCCCTTTCGTTG
GGAATAGCATCTTGAGTCGGGCTGTTACTTCAGCTTTAAAAGAGGAGGGTGAAATCCTTTATCTTACGGCTACCTCGACT
AAAGAGCTTGATTTGAAAGTGAAAAGAGGTGATATTGAGAAACTAACATTACCTAGACGTTTCCATAATCAACCCTTGAT
TGTCCCTAAATTTAAACTTATCCTTAATTTGGAAGAATCATTACAAAAAAAGCGTCTCCCTATTCCGTTATTGAACATGA
TTCGAAGGCAAAGAAAAACAAATTACCAACTATTAATTTTTCATCCCATTATAGATAAGGGTGAGGAGTTTTTTCGTTTA
TTAGCAACTAAACTGAGGAATGAAAAGATTGCCTATGTCTCAAGTCAATCCGATCATAGAAAGCAGATAATTGAACAATT
TAGGAAATCAGAAATATCTATTTTAATCACGACAACAATCCTAGAAAGAGGCGTAACCTTTCCAGGTGTAGATGTGTTTG
TGCTTTTGTCTCATCACAAATTATTTAATGCGTCTAGCCTTATACAAATTTCGGGACGCGTTGGAAGATCTCTTGATCGC
CCAACGGGGCAGCTATTTTTCTTACATCAAGGAATTAGCATAGATATGTTAAAAGCCAAAAAAGAAATTATCAGGATGAA
TAGGGAGGCATATGGACAATAG

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(95-209)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae Rx1

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae D39

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae R6

54.009

97.921

0.529
  comFA/cflA Streptococcus mitis NCTC 12261

53.538

97.921

0.524
  comFA/cflA Streptococcus mitis SK321

53.302

97.921

0.522
  comFA Lactococcus lactis subsp. cremoris KW2

49.367

91.224

0.45
  comFA Latilactobacillus sakei subsp. sakei 23K

37.813

100

0.383

Multiple sequence alignment