Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   CGZ53_RS04050 Genome accession   NZ_CP022435
Coordinates   770109..771338 (+) Length   409 a.a.
NCBI ID   WP_012658290.1    Uniprot ID   A0A2X4EFJ3
Organism   Streptococcus uberis strain NZ01     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 765109..776338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGZ53_RS04025 (CGZ53_04025) - 765831..767117 (-) 1287 WP_233845138.1 hydroxymethylglutaryl-CoA reductase, degradative -
  CGZ53_RS04030 (CGZ53_04030) - 767104..768279 (-) 1176 WP_100911998.1 hydroxymethylglutaryl-CoA synthase -
  CGZ53_RS04035 (CGZ53_04035) - 768474..769313 (+) 840 WP_100911999.1 thymidylate synthase -
  CGZ53_RS04040 (CGZ53_04040) - 769393..769890 (+) 498 WP_012658288.1 dihydrofolate reductase -
  CGZ53_RS04050 (CGZ53_04050) clpX 770109..771338 (+) 1230 WP_012658290.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  CGZ53_RS04055 (CGZ53_04055) yihA 771349..771948 (+) 600 WP_012658291.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  CGZ53_RS04060 (CGZ53_04060) - 772101..772823 (+) 723 WP_100912000.1 hypothetical protein -
  CGZ53_RS04065 (CGZ53_04065) - 772893..774995 (-) 2103 WP_100912001.1 AAA family ATPase -
  CGZ53_RS04070 (CGZ53_04070) rplJ 775396..775896 (+) 501 WP_012658294.1 50S ribosomal protein L10 -
  CGZ53_RS04075 (CGZ53_04075) rplL 775962..776327 (+) 366 WP_012658295.1 50S ribosomal protein L7/L12 -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45059.60 Da        Isoelectric Point: 4.4892

>NTDB_id=239383 CGZ53_RS04050 WP_012658290.1 770109..771338(+) (clpX) [Streptococcus uberis strain NZ01]
MAGNRSTDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVLLSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALAVAVYNHYKRISFSESRDEEEVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDEDASYMQEIISDDIQKFGLIPEFIGRLPVVAALEQLNIDDLIQI
LTVPKNALVKQYQALLSYDGVELSFDQDALEAIAAKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVVKVRITKESVNG
DAKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=239383 CGZ53_RS04050 WP_012658290.1 770109..771338(+) (clpX) [Streptococcus uberis strain NZ01]
ATGGCAGGAAATAGAAGTACTGATATTAAGGTACATTGTTCATTTTGTGGTAAAAGCCAAGATGAAGTTAAAAAAATAAT
CGCAGGTAATAATGTTTTTATCTGTAATGAATGTGTTCTTTTATCACAAGAAATTATTAAAGAAGAGTTAGCAGAAGAAG
TCTTAGCTGATTTAACAGAAGTTCCAAAACCAAAGGAACTTTTAGATGTTTTAAACCAATATGTAGTCGGTCAGGACCGT
GCTAAAAGAGCATTGGCTGTTGCGGTTTACAATCATTATAAACGCATTTCATTTTCTGAAAGTCGTGATGAAGAGGAAGT
TGAATTGCAAAAATCAAACATCTTGATGATTGGGCCAACAGGATCTGGTAAGACCTTCTTAGCCCAAACCTTGGCAAAAA
GTTTAAATGTGCCTTTTGCCATTGCTGATGCAACATCATTAACAGAAGCAGGCTATGTCGGAGAAGATGTTGAAAATATT
TTGTTGAAACTTATCCAAGCTGCTGATTACAATGTTGAACGAGCAGAACGTGGTATTATTTACGTAGACGAAATAGACAA
AATTGCCAAAAAAGGTGAGAATGTCTCTATCACACGTGATGTATCAGGAGAAGGAGTTCAACAAGCCTTGTTGAAAATCA
TTGAAGGGACAGTTGCATCTGTTCCACCTCAAGGAGGCCGGAAACACCCTAATCAAGAGATGATTCAAATTGATACCAAA
AATATTTTATTTATCGTTGGCGGTGCTTTTGATGGCATTGAAGAAATTGTCAAACAGCGATTGGGTGAAAAAATCATTGG
CTTTGGTCAAAATTCCCGTAAGATTGATGAAGATGCTTCTTATATGCAAGAAATCATTTCTGATGATATTCAAAAATTCG
GTCTTATACCAGAATTCATTGGTCGCCTACCAGTTGTAGCTGCTTTAGAACAGCTCAACATAGATGACCTCATTCAAATT
TTGACAGTTCCGAAAAATGCTTTGGTTAAACAATATCAAGCCCTATTGTCATATGATGGTGTTGAATTGTCATTTGATCA
AGATGCTTTAGAAGCTATTGCGGCGAAAGCTATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCCATTATTGAAGAAA
CCATGTTAGATATTATGTTTGAAATTCCTAGTCAGGAAGATGTAGTCAAAGTACGTATTACCAAGGAATCTGTCAATGGT
GACGCAAAACCGATTTTAGAAACAGCGTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X4EFJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.264

100

0.883
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.603

98.044

0.575

Multiple sequence alignment