Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   CGZ53_RS02970 Genome accession   NZ_CP022435
Coordinates   540414..541772 (+) Length   452 a.a.
NCBI ID   WP_012658078.1    Uniprot ID   B9DRG9
Organism   Streptococcus uberis strain NZ01     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 535414..546772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGZ53_RS02940 (CGZ53_02930) - 535431..536438 (+) 1008 WP_100911953.1 DUF3114 domain-containing protein -
  CGZ53_RS02945 (CGZ53_02935) - 536469..537116 (-) 648 WP_012658074.1 amino acid ABC transporter permease -
  CGZ53_RS02950 (CGZ53_02940) - 537132..537833 (-) 702 WP_012658075.1 amino acid ABC transporter permease -
  CGZ53_RS02955 (CGZ53_02945) - 537848..538663 (-) 816 WP_012658076.1 transporter substrate-binding domain-containing protein -
  CGZ53_RS02960 (CGZ53_02950) - 538677..539456 (-) 780 WP_012658077.1 amino acid ABC transporter ATP-binding protein -
  CGZ53_RS02965 (CGZ53_02955) vicR 539711..540421 (+) 711 WP_015912156.1 response regulator YycF Regulator
  CGZ53_RS02970 (CGZ53_02960) vicK 540414..541772 (+) 1359 WP_012658078.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CGZ53_RS02975 (CGZ53_02965) vicX 541776..542585 (+) 810 WP_012658079.1 MBL fold metallo-hydrolase Regulator
  CGZ53_RS02980 (CGZ53_02970) rnc 542745..543437 (+) 693 WP_012658080.1 ribonuclease III -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 51569.95 Da        Isoelectric Point: 4.8795

>NTDB_id=239376 CGZ53_RS02970 WP_012658078.1 540414..541772(+) (vicK) [Streptococcus uberis strain NZ01]
MTENLIGNLSLFELSILLLLIFVAAYFIYLAVRDYRNAKIIRQMSHKIRDLINGRYTDEINEKADIELIELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRTGQIMMINETAQKQLNISKEEALLMNITDLLGQDTPYTYRELVSKTPI
VTLNRRDETGEFITLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTALAVEMTNFTAFMTSILNRFDLVRNQNTVSGKSYEIIRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKIRVKMKTTDSQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIVKQHNGFIWAKSDYGKGSTFTIVLPYEKDVVAGTDDEWEDDID

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=239376 CGZ53_RS02970 WP_012658078.1 540414..541772(+) (vicK) [Streptococcus uberis strain NZ01]
ATGACTGAGAACCTAATCGGAAATTTATCGTTATTCGAACTTTCAATCTTATTATTACTTATTTTTGTTGCTGCATATTT
TATTTATTTAGCAGTTCGTGACTATCGAAATGCCAAAATTATTCGGCAAATGAGTCATAAAATCCGTGACCTAATCAATG
GTCGTTACACGGATGAAATCAATGAAAAAGCTGATATTGAGCTCATTGAACTTTCAGAGCAACTCAATGATTTATCGGAT
GTCTTTCGATTGACCCATGAAAATCTTGCCCAGGAAAAAAATCGCTTAGCCAGTATTTTGGCCTACATGAGTGATGGGGT
TTTGGCAACAGACCGAACTGGTCAAATCATGATGATTAACGAAACCGCCCAAAAACAATTGAATATTTCGAAAGAAGAAG
CCCTTTTAATGAATATCACGGATTTGTTAGGGCAAGACACTCCCTATACCTACCGGGAATTGGTTTCCAAAACACCGATT
GTTACCTTGAATAGACGCGATGAGACTGGTGAATTTATCACCCTCAGGCTGCGCTTTGCCTTGAATAGAAGAGAAAGTGG
ATTCATTTCGGGGCTTGTTGTCGTCCTACATGACACTACCGAACAGGAAAAAGAAGAACGTGAGCGTCGCCTCTTTGTTT
CGAATGTTAGTCACGAATTAAGAACGCCATTGACATCAGTCAAATCCTATTTGGAAGCCCTGGATGAGGGTGCCTTAAAA
GAAGATATCGCACCAAGTTTCATCAAAGTTTCACTAGATGAAACCAATCGGATGATGCGAATGATTTCGGACTTGTTAAA
CCTGTCTCGTATTGATAACCAAGTCACAGCTCTAGCAGTTGAAATGACCAATTTCACAGCCTTTATGACTTCTATACTAA
ATCGTTTTGATTTAGTGAGAAACCAAAATACAGTTTCAGGGAAAAGCTATGAAATTATACGAGATTATCCTATTACTTCT
GTTTGGCTAGAAATTGACAATGATAAAATGACACAAGTCATTGAAAACATTTTAAATAATGCTATCAAATATTCACCTGA
TGGTGGTAAAATTCGTGTTAAGATGAAAACAACAGATAGTCAATTGATTATCTCTATTTCGGATCAAGGATTAGGAATTC
CAAAGAAAGATCTTCCTTTGATTTTTGACCGATTTTATCGGGTGGATAAAGCACGCAGTCGTGCACAAGGTGGAACAGGT
TTAGGACTTGCCATTGCTAAAGAAATTGTAAAACAACATAATGGTTTTATATGGGCAAAAAGTGACTATGGCAAAGGCTC
GACCTTTACAATTGTATTGCCATATGAAAAAGATGTTGTTGCAGGAACAGATGATGAATGGGAGGATGATATTGACTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DRG9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.608

91.372

0.673
  micB Streptococcus pneumoniae Cp1015

65.882

94.027

0.619

Multiple sequence alignment