Detailed information NTG0023905

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: TRNA_RS31050
• Genome accession: NC_006270
• Coordinates: 1888366..1890975 (+)
• Length: 869 a.a.
• NCBI ID: WP_011197985.1
• Uniprot ID: Q65JE2
• Organism: Bacillus licheniformis DSM 13 = ATCC 14580
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1883366..1895975

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TRNA_RS31030 (BL03659)	-	1884183..1885358 (+)	1176	WP_011197984.1	glycine C-acetyltransferase	-
TRNA_RS31035 (BL03660)	miaB	1885502..1887031 (+)	1530	WP_003181965.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
TRNA_RS31040 (BL03661)	ymcA	1887033..1887464 (+)	432	WP_003181967.1	RicAFT regulatory complex protein RicA family protein	Regulator
TRNA_RS31045 (BL03662)	cotE	1887707..1888255 (+)	549	WP_003181968.1	outer spore coat protein CotE	-
TRNA_RS31050 (BL03663)	hexA	1888366..1890975 (+)	2610	WP_011197985.1	DNA mismatch repair protein MutS	Machinery gene
TRNA_RS31055 (BL03664)	hexB	1890993..1892903 (+)	1911	WP_003181972.1	DNA mismatch repair endonuclease MutL	Machinery gene
TRNA_RS31060 (BL03665)	-	1893237..1893518 (+)	282	WP_003181975.1	putative quinol monooxygenase	-
TRNA_RS31065 (BL03666)	-	1893700..1894227 (+)	528	WP_003181977.1	pre-toxin TG domain-containing protein	-
TRNA_RS43250	-	1894224..1894472 (+)	249	WP_080508521.1	HNH/endonuclease VII fold putative polymorphic toxin	-
TRNA_RS31070 (BL03667)	-	1894528..1894965 (+)	438	WP_011201654.1	hypothetical protein	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98514.94 Da
• Isoelectric Point: 5.3661

>NTDB_id=23905 TRNA_RS31050 WP_011197985.1 1888366..1890975(+) (hexA) [Bacillus licheniformis DSM 13 = ATCC 14580]
MAGYTPMIQQYLKIKAEYQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGSSERIPMCGVPYHSCSSYIEQLIKK
GYKVAICEQVEDPKSAKGVVKREVVQLITPGTVMDGKGIHENENNFIASVSKFQHTYGLAFSDLTTGENLVTAIERLDDV
VSEIYSVGAREIVVSRNLDEKDVAMLKERCGATISFEDEQADEVPGIVNGLGSKELVDTFMRLYVYLKRTQKRSLDHLQN
VQAYELEEAMKIDLYSKRNLELTETIRSKNKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRKGQIEERQEIVETLIAHLF
EREDLRERLKEVYDLERLAGRVAYGNVNARDLIQLKESLKQVPAIKQLVGSLDHPKAKARAEKIDPCGDLLNLLEDALYE
NPPLSLKEGNLIKDGYHAKLDEYRDASKNGKDWIARLEQQEREYTGIRSLKVGFNKVFGYYIEVTKANIHLLEEGRYERK
QTLTNAERYITPELKEKEALILEAENNICELEYELFSELRSKVKEYIPRLQQLAKMMSELDVLQCFATISENRHYVKPEF
SDDVVQVIDGRHPVVEKVMDSQSYVPNSCEMGKGRQMLLITGPNMSGKSTYMRQMALISILAQIGCFVPAKKAVLPIFDQ
IFTRIGAADDLISGQSTFMVEMLEAKNAIVHATKNSLILFDEIGRGTSTYDGMALAQAIIEYVHEHIGAKTLFSTHYHEL
TSLEEKLDDLKNVHVRAEEYEGKVVFLHQIKEGAADKSYGIHVAQLAELPDGLISRAKTILKELESGAKEAAPSTAPNMV
KEAAEEAAATVADQPAQLSFFETDKPIEKETKLSKKEQAVLAEFKAMDLLDMTPIQVMNELYRLQKKLK

Nucleotide

• Length: 2610 bp

>NTDB_id=23905 TRNA_RS31050 WP_011197985.1 1888366..1890975(+) (hexA) [Bacillus licheniformis DSM 13 = ATCC 14580]
ATGGCAGGCTACACGCCTATGATACAGCAATATTTAAAGATTAAGGCAGAGTATCAGGATGCCTTTTTATTTTTTCGTCT
TGGCGACTTTTATGAGATGTTTTTTGAAGATGCAAAAAAGGCGTCTCAGGAGCTCGAAATCACGCTGACGAGCAGGGACG
GAGGATCAAGCGAAAGAATTCCGATGTGCGGGGTTCCTTATCATTCCTGCTCTTCGTATATCGAACAGCTCATTAAAAAA
GGCTATAAAGTCGCGATCTGTGAACAGGTGGAGGACCCTAAATCGGCCAAAGGAGTCGTCAAAAGGGAAGTCGTGCAGCT
GATCACACCCGGCACCGTGATGGACGGCAAAGGGATTCATGAAAATGAAAACAACTTTATCGCCTCTGTCAGTAAATTTC
AGCATACATACGGGCTCGCTTTTTCTGATTTGACGACAGGCGAGAATTTAGTAACGGCTATCGAAAGGCTTGATGATGTC
GTTTCCGAAATTTACTCTGTCGGAGCAAGGGAAATCGTCGTCAGCCGCAACCTTGACGAGAAAGACGTCGCAATGCTGAA
AGAGCGCTGCGGCGCCACGATCTCTTTCGAGGATGAACAAGCGGATGAAGTGCCTGGCATTGTGAACGGACTGGGGTCCA
AAGAGCTTGTCGATACGTTTATGAGGCTTTACGTCTACTTGAAGCGGACGCAGAAAAGAAGCCTCGACCACCTTCAAAAC
GTTCAGGCCTACGAGCTCGAAGAAGCGATGAAAATCGATTTGTACTCGAAACGCAATCTTGAACTGACGGAAACGATCCG
TTCGAAAAACAAAAAAGGCTCGCTTCTTTGGCTTTTGGATGAAACGAAAACGGCCATGGGAGGGCGGCTGTTAAAGCAAT
GGATCGACAGGCCGCTGATCAGAAAGGGACAGATCGAAGAGCGCCAGGAAATCGTTGAAACGCTGATCGCCCATCTGTTT
GAGCGGGAAGATTTGCGCGAACGGCTGAAGGAAGTATACGACCTCGAGCGGCTCGCCGGAAGGGTCGCATACGGCAACGT
CAACGCCAGAGATTTGATCCAGCTGAAGGAATCGCTGAAACAAGTCCCGGCCATCAAACAGCTTGTCGGCTCCCTCGACC
ATCCGAAAGCAAAAGCGCGCGCCGAGAAAATCGATCCGTGCGGCGATCTTTTGAATCTTTTGGAAGACGCGCTATACGAG
AATCCGCCTCTTTCATTAAAAGAGGGGAACTTAATCAAAGACGGCTACCACGCGAAACTGGATGAATACAGGGACGCAAG
CAAGAACGGAAAAGACTGGATCGCAAGGCTTGAGCAGCAGGAACGCGAGTACACGGGAATCCGCTCTTTAAAAGTCGGCT
TTAACAAGGTGTTCGGCTATTATATTGAAGTGACGAAAGCGAACATCCATCTGCTTGAAGAAGGCCGCTATGAACGGAAG
CAGACGCTGACCAATGCAGAACGCTACATCACGCCGGAGCTGAAAGAAAAAGAAGCCCTGATTCTCGAAGCGGAAAACAA
TATTTGCGAGCTGGAGTATGAGCTGTTTTCCGAGCTTCGCAGCAAGGTGAAGGAATATATCCCGCGCTTGCAGCAGCTGG
CAAAAATGATGAGCGAGCTTGATGTGCTCCAATGTTTTGCGACGATCAGCGAAAACCGGCACTATGTTAAGCCGGAGTTT
TCCGATGATGTCGTTCAGGTGATCGACGGACGGCATCCGGTCGTAGAAAAGGTGATGGACAGCCAGTCTTACGTTCCGAA
CAGCTGTGAAATGGGCAAAGGCAGGCAGATGCTTTTAATCACCGGGCCGAATATGTCCGGGAAAAGCACGTATATGAGAC
AGATGGCGCTGATCTCCATTTTGGCGCAGATCGGCTGCTTTGTTCCTGCGAAAAAAGCGGTGCTGCCGATCTTTGATCAG
ATCTTTACGAGAATTGGCGCAGCGGATGATCTTATATCCGGACAGAGCACGTTTATGGTGGAAATGCTTGAAGCCAAAAA
CGCGATCGTCCATGCGACGAAAAACAGCTTGATTTTATTTGACGAAATCGGCCGGGGTACGTCCACTTACGACGGAATGG
CGCTTGCACAAGCGATCATCGAGTACGTTCACGAGCACATCGGCGCGAAGACTTTATTTTCCACTCACTACCACGAGCTG
ACGTCCCTTGAAGAAAAGCTGGACGATTTGAAGAATGTCCACGTTCGTGCGGAAGAATACGAAGGAAAGGTCGTTTTCCT
TCACCAGATAAAAGAAGGAGCAGCAGATAAAAGCTACGGTATCCATGTCGCGCAGCTGGCTGAATTGCCCGACGGTTTGA
TCAGCAGGGCGAAAACGATCCTGAAAGAACTTGAATCCGGCGCAAAAGAAGCCGCTCCATCAACGGCACCGAATATGGTA
AAAGAGGCGGCGGAAGAAGCCGCGGCGACTGTTGCAGATCAACCGGCCCAGCTGTCATTTTTTGAGACGGACAAGCCAAT
AGAAAAAGAGACGAAGCTCTCCAAAAAAGAGCAGGCTGTTTTAGCCGAATTTAAAGCGATGGATCTGCTCGATATGACGC
CTATACAAGTCATGAATGAACTGTACAGGCTGCAAAAAAAATTAAAGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (598-785)

• MutS domain III (MutS_III) (258-547)

• MutS domain I (MutS_I) (5-116)

• MutS domain II (MutS_II) (125-239)

• MutS family domain IV (MutS_IV) (415-506)

3D structure

• AlphaFold DB: Q65JE2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	49.017	99.54	0.488
mutS	Pseudomonas stutzeri strain ATCC 17587	37.528	100	0.381