Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   QMA0248_RS06545 Genome accession   NZ_CP022392
Coordinates   1348456..1349814 (-) Length   452 a.a.
NCBI ID   WP_003101335.1    Uniprot ID   -
Organism   Streptococcus iniae strain QMA0248     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1343456..1354814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMA0248_RS06535 (QMA0248_1323) rnc 1346848..1347540 (-) 693 WP_003101331.1 ribonuclease III -
  QMA0248_RS06540 (QMA0248_1324) vicX 1347643..1348452 (-) 810 WP_003101333.1 MBL fold metallo-hydrolase Regulator
  QMA0248_RS06545 (QMA0248_1325) vicK 1348456..1349814 (-) 1359 WP_003101335.1 cell wall metabolism sensor histidine kinase VicK Regulator
  QMA0248_RS06550 (QMA0248_1326) vicR 1349807..1350517 (-) 711 WP_003101337.1 response regulator YycF Regulator
  QMA0248_RS06555 (QMA0248_1327) - 1350774..1351571 (+) 798 WP_003101338.1 amino acid ABC transporter ATP-binding protein -
  QMA0248_RS06560 (QMA0248_1328) - 1351568..1352386 (+) 819 WP_003101339.1 transporter substrate-binding domain-containing protein -
  QMA0248_RS06565 (QMA0248_1329) - 1352401..1353102 (+) 702 WP_003101340.1 amino acid ABC transporter permease -
  QMA0248_RS06570 (QMA0248_1330) - 1353118..1353765 (+) 648 WP_003101341.1 amino acid ABC transporter permease -
  QMA0248_RS06575 (QMA0248_1331) - 1353803..1354810 (-) 1008 WP_003101345.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 51565.95 Da        Isoelectric Point: 4.8298

>NTDB_id=238998 QMA0248_RS06545 WP_003101335.1 1348456..1349814(-) (vicK) [Streptococcus iniae strain QMA0248]
MTKDIIGNLSLFELAILSLLIFVAVYFVHLALRDYRNAKIIRQMSHKIRDLINGRYTDDINQKADIELMELSEQLNDLSD
VFRLSHENLAQEKNRLASILAYMSDGVLATDRSGQILMINETAQKQLNLSREEALQKNITDLLDNDTPYTYRELVSKTPV
VTLNRRDEMGEFITLRLRFALNRRESGFISGLVVVLHDMTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EEIAPNFIKVSLDETNRMMRMISDLLNLSRIDNNVTTLAVEMTNFTAFMTSILNRFDLVKTQNTVAGKSYEIIRDYPITS
VWVEIDNDKMTQVIENILNNAIKYSPDGGKIGVKMKTTDTQLIISISDEGLGIPKKDLPLIFDLFYRVDKARSRAQGGTG
LGLAIAKEIIKQHNGFIWAKSDYGKGSTFTIVLPYEKDVMTDGEDDWEDDID

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=238998 QMA0248_RS06545 WP_003101335.1 1348456..1349814(-) (vicK) [Streptococcus iniae strain QMA0248]
ATGACTAAAGATATTATTGGTAACTTATCCTTATTTGAATTAGCAATTCTGTCTCTTCTTATTTTTGTTGCTGTTTATTT
TGTCCACTTGGCTCTTCGTGATTATCGAAACGCTAAGATTATTAGACAAATGAGCCATAAAATACGGGACTTGATTAATG
GTCGTTATACTGATGACATTAATCAAAAGGCAGATATTGAATTAATGGAGCTGTCTGAACAGTTAAACGACTTATCAGAT
GTTTTTCGCTTAAGCCATGAAAATTTAGCCCAGGAAAAAAATCGTTTGGCCAGTATTCTTGCCTATATGAGCGATGGTGT
CTTGGCAACTGACCGATCAGGTCAAATTTTGATGATTAATGAAACAGCACAAAAACAATTGAATTTAAGCCGTGAAGAAG
CTCTGCAAAAAAACATTACAGATTTACTTGATAATGACACTCCTTACACCTATCGGGAATTAGTGTCTAAAACACCTGTT
GTGACCTTAAACCGACGTGATGAAATGGGAGAATTTATAACCTTAAGATTGCGTTTTGCCTTAAATCGCCGTGAAAGTGG
TTTTATTTCAGGATTAGTTGTCGTTTTACATGACATGACCGAGCAAGAAAAAGAAGAACGAGAACGTCGTCTCTTTGTTT
CTAATGTTAGTCATGAATTAAGAACGCCATTAACATCTGTTAAGTCATATTTAGAGGCTTTGGATGAAGGTGCCTTAAAA
GAAGAAATTGCCCCCAATTTTATCAAGGTTTCTTTAGATGAGACAAATCGTATGATGCGGATGATTTCTGATCTTTTGAA
TTTATCAAGAATTGACAATAATGTAACGACCTTAGCTGTTGAAATGACTAACTTTACAGCCTTTATGACCTCTATTTTAA
ACCGTTTTGACTTGGTTAAAACGCAAAATACAGTTGCAGGGAAAAGCTATGAAATTATTCGAGATTATCCCATTACATCT
GTATGGGTTGAGATTGATAATGATAAAATGACACAAGTCATTGAAAATATTCTTAACAATGCCATTAAGTATTCCCCAGA
TGGTGGAAAGATTGGTGTTAAGATGAAAACTACTGACACGCAATTGATTATCTCTATTTCTGATGAAGGATTGGGCATAC
CTAAAAAAGACTTGCCATTGATTTTTGATCTTTTTTACCGTGTTGATAAGGCTAGAAGTCGCGCCCAAGGTGGTACTGGC
TTAGGCTTGGCTATTGCAAAAGAAATTATTAAGCAACACAATGGCTTTATTTGGGCAAAAAGTGACTATGGCAAGGGCTC
TACATTTACCATTGTCTTGCCATATGAAAAAGATGTGATGACAGATGGAGAAGATGATTGGGAGGATGATATAGACTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

72.881

91.372

0.666
  micB Streptococcus pneumoniae Cp1015

65.882

94.027

0.619

Multiple sequence alignment