Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   QMA0248_RS05240 Genome accession   NZ_CP022392
Coordinates   1075447..1076676 (-) Length   409 a.a.
NCBI ID   WP_003099812.1    Uniprot ID   -
Organism   Streptococcus iniae strain QMA0248     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1056088..1078316 1075447..1076676 within 0


Gene organization within MGE regions


Location: 1056088..1078316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMA0248_RS05140 (QMA0248_1039) - 1056088..1057242 (-) 1155 WP_003099772.1 ABC transporter ATP-binding protein -
  QMA0248_RS05145 (QMA0248_1040) murB 1057277..1058170 (-) 894 WP_003099774.1 UDP-N-acetylmuramate dehydrogenase -
  QMA0248_RS05150 (QMA0248_1041) - 1058425..1059591 (+) 1167 WP_003099776.1 IS30 family transposase -
  QMA0248_RS05155 (QMA0248_1042) folK 1059843..1060334 (-) 492 WP_003099778.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
  QMA0248_RS05160 (QMA0248_1043) folB 1060331..1060690 (-) 360 WP_003099779.1 dihydroneopterin aldolase -
  QMA0248_RS05165 (QMA0248_1044) folP 1060697..1061497 (-) 801 WP_003099781.1 dihydropteroate synthase -
  QMA0248_RS05170 (QMA0248_1045) folE 1061507..1062070 (-) 564 WP_003099782.1 GTP cyclohydrolase I FolE -
  QMA0248_RS05175 (QMA0248_1046) - 1062099..1063358 (-) 1260 WP_003099784.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  QMA0248_RS05180 (QMA0248_1047) thrB 1063442..1064302 (-) 861 WP_003099786.1 homoserine kinase -
  QMA0248_RS05185 (QMA0248_1048) - 1064304..1065590 (-) 1287 WP_016356020.1 homoserine dehydrogenase -
  QMA0248_RS05190 (QMA0248_1049) - 1065775..1066695 (+) 921 WP_003099793.1 polysaccharide deacetylase family protein -
  QMA0248_RS05195 (QMA0248_1050) - 1066955..1068130 (+) 1176 WP_003099056.1 IS256 family transposase -
  QMA0248_RS05205 (QMA0248_1053) tnpA 1069648..1070088 (-) 441 WP_003099798.1 IS200/IS605 family transposase -
  QMA0248_RS05210 (QMA0248_1054) rplL 1070311..1070676 (-) 366 WP_003099800.1 50S ribosomal protein L7/L12 -
  QMA0248_RS05215 (QMA0248_1055) rplJ 1070740..1071240 (-) 501 WP_003099802.1 50S ribosomal protein L10 -
  QMA0248_RS05220 (QMA0248_1056) - 1071504..1072457 (-) 954 WP_003098612.1 IS30 family transposase -
  QMA0248_RS05225 - 1072603..1073945 (-) 1343 Protein_977 IS3 family transposase -
  QMA0248_RS05230 (QMA0248_1060) - 1074017..1074730 (-) 714 WP_003099809.1 hypothetical protein -
  QMA0248_RS05235 (QMA0248_1061) yihA 1074838..1075437 (-) 600 WP_003099810.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  QMA0248_RS05240 (QMA0248_1062) clpX 1075447..1076676 (-) 1230 WP_003099812.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  QMA0248_RS05250 (QMA0248_1064) - 1076901..1077398 (-) 498 WP_003099817.1 dihydrofolate reductase -
  QMA0248_RS05255 (QMA0248_1065) - 1077477..1078316 (-) 840 WP_017794807.1 thymidylate synthase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45151.78 Da        Isoelectric Point: 4.4847

>NTDB_id=238991 QMA0248_RS05240 WP_003099812.1 1075447..1076676(-) (clpX) [Streptococcus iniae strain QMA0248]
MAVNRTNDIKVHCSFCGKDQDEVKKIIAGNNVFICDECVALSQEIIKEELAEEVLADLTEVPKPKELLDILNQYVVGQDH
AKKALAVAVYNHYKRVSFTESRDEDEVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTEASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDEDASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLTVADLIQI
LTEPRNALVKQYQALLSYDGVELEFEKAALEAIAAKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVIKVRITKDSVDG
LKKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=238991 QMA0248_RS05240 WP_003099812.1 1075447..1076676(-) (clpX) [Streptococcus iniae strain QMA0248]
ATGGCAGTTAATCGTACAAACGATATTAAGGTCCATTGTTCATTTTGTGGCAAGGACCAAGATGAAGTTAAAAAAATTAT
TGCAGGGAACAATGTTTTCATCTGTGATGAATGTGTTGCATTATCTCAAGAAATTATAAAAGAAGAATTAGCAGAGGAAG
TATTAGCTGATTTAACGGAAGTTCCAAAACCAAAAGAACTTTTAGATATTTTAAATCAATATGTTGTTGGTCAAGACCAT
GCTAAAAAGGCTTTAGCAGTAGCAGTTTATAACCATTATAAGCGTGTTTCGTTTACAGAAAGTCGCGATGAAGATGAAGT
GGAATTGCAAAAGTCAAATATTCTCATGATTGGCCCAACTGGTTCAGGAAAAACCTTCTTGGCACAAACTTTGGCAAAAA
GTTTAAATGTACCATTTGCCATTGCGGATGCTACTTCATTAACTGAAGCTGGCTATGTCGGCGAAGATGTTGAGAATATT
CTGCTAAAATTAATTCAAGCAGCTGATTATAATGTAGAACGTGCAGAACGTGGCATTATTTATGTTGATGAAATTGATAA
AATTGCTAAAAAAGGGGAAAATGTTTCCATTACACGCGATGTCTCTGGTGAAGGTGTTCAACAAGCCCTGCTAAAAATTA
TTGAAGGCACAGAAGCAAGTGTTCCACCTCAAGGTGGACGTAAACACCCTAATCAAGAGATGATTCAAATTGATACGAAA
AATATTTTGTTCATCGTTGGTGGCGCTTTTGATGGCATTGAAGAAATTGTTAAACAGCGTCTTGGAGAAAAAATTATTGG
TTTTGGCCAAAATAGCCGTAAAATTGATGAAGATGCTTCATATATGCAAGAAATTATCGCAGAAGACATTCAAAAATTTG
GCCTTATTCCAGAATTTATTGGACGCTTACCTGTTGTTGCAGCCTTAGAACAGTTAACAGTTGCTGACCTGATTCAAATT
TTAACAGAACCAAGAAATGCTCTTGTTAAACAATACCAAGCTCTTTTATCTTATGATGGTGTTGAACTTGAATTTGAAAA
GGCTGCTTTGGAAGCTATTGCTGCAAAAGCTATAGAACGTAAAACTGGTGCGCGTGGCCTTCGTTCAATCATTGAAGAAA
CCATGCTTGACATTATGTTTGAAATCCCTAGTCAAGAAGATGTTATTAAGGTTCGCATTACTAAGGACTCTGTGGATGGG
CTTAAAAAACCTATTTTGGAAACGGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.775

100

0.878
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.895

97.555

0.565

Multiple sequence alignment