Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CFN12_RS02625 Genome accession   NZ_CP022290
Coordinates   528988..529557 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain EDCC5458     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 523988..534557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFN12_RS02600 (CFN12_02575) cysE 525201..525848 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  CFN12_RS02605 (CFN12_02580) cysS 525832..527232 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  CFN12_RS02610 (CFN12_02585) - 527225..527629 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  CFN12_RS02615 (CFN12_02590) rlmB 527637..528383 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CFN12_RS02620 (CFN12_02595) - 528383..528907 (+) 525 WP_000664738.1 NYN domain-containing protein -
  CFN12_RS02625 (CFN12_02600) sigH 528988..529557 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  CFN12_RS02630 (CFN12_02605) rpmG 529672..529815 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  CFN12_RS02635 (CFN12_02610) secE 529871..530053 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  CFN12_RS02640 (CFN12_02615) nusG 530066..530614 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  CFN12_RS02645 (CFN12_02620) rplK 530795..531217 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  CFN12_RS02650 (CFN12_02625) rplA 531425..532117 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  CFN12_RS02660 (CFN12_02635) rplJ 532389..532889 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  CFN12_RS02665 (CFN12_02640) rplL 532932..533300 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  CFN12_RS02670 (CFN12_02645) - 533475..534083 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=238038 CFN12_RS02625 WP_000872873.1 528988..529557(+) (sigH) [Staphylococcus aureus strain EDCC5458]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=238038 CFN12_RS02625 WP_000872873.1 528988..529557(+) (sigH) [Staphylococcus aureus strain EDCC5458]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment