Detailed information NTG0236648

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CEP67_RS03860
• Genome accession: NZ_CP022096
• Coordinates: 807231..808274 (-)
• Length: 347 a.a.
• NCBI ID: WP_002472963.1
• Uniprot ID: A0A1Z3TZK4
• Organism: Staphylococcus pettenkoferi strain FDAARGOS_288
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 802231..813274

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CEP67_RS03830 (CEP67_03835)	-	803144..803344 (-)	201	WP_002472952.1	DUF1128 family protein	-
CEP67_RS03835 (CEP67_03840)	-	803479..803943 (+)	465	WP_088606345.1	low molecular weight protein-tyrosine-phosphatase	-
CEP67_RS03840 (CEP67_03845)	-	803948..804250 (+)	303	WP_002472981.1	hypothetical protein	-
CEP67_RS03845 (CEP67_03850)	-	804508..805740 (+)	1233	WP_002472988.1	YihY/virulence factor BrkB family protein	-
CEP67_RS03850 (CEP67_03855)	-	805950..806519 (+)	570	WP_002472972.1	beta-class carbonic anhydrase	-
CEP67_RS03855 (CEP67_03860)	vraR	806612..807241 (-)	630	WP_040806996.1	response regulator transcription factor	Regulator
CEP67_RS03860 (CEP67_03865)	vraS	807231..808274 (-)	1044	WP_002472963.1	sensor histidine kinase	Regulator
CEP67_RS03865 (CEP67_03870)	liaF	808271..808972 (-)	702	WP_002472955.1	cell wall-active antibiotics response protein LiaF	-
CEP67_RS03870 (CEP67_03875)	-	809159..809554 (-)	396	WP_002472969.1	hypothetical protein	-
CEP67_RS03875 (CEP67_03880)	map	809715..810479 (-)	765	WP_002472950.1	type I methionyl aminopeptidase	-
CEP67_RS03880 (CEP67_03885)	-	810636..811625 (+)	990	WP_088606346.1	FUSC family protein	-
CEP67_RS03885 (CEP67_03890)	-	811745..812467 (-)	723	WP_002472968.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40013.42 Da
• Isoelectric Point: 5.8559

>NTDB_id=236648 CEP67_RS03860 WP_002472963.1 807231..808274(-) (vraS) [Staphylococcus pettenkoferi strain FDAARGOS_288]
MNHYIRAIGSMLILVYSMLFAFLFIDKIFVNIIYFQGMFYTQIFGIPVFLFLNIVIILLCIIVGSVLAYKINQQNHWLQE
QIERSIEGETVGINDQNIELYNETIALYQTLVPLNQEVHKLRMKTQNLTNESYNINDKKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESTLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHQI
EDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTIELFNKEDYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAN
FHIVSLPDSGTRIEVKAPLNKEELSDD

Nucleotide

• Length: 1044 bp

>NTDB_id=236648 CEP67_RS03860 WP_002472963.1 807231..808274(-) (vraS) [Staphylococcus pettenkoferi strain FDAARGOS_288]
GTGAATCACTACATAAGAGCCATAGGATCGATGTTAATCCTCGTCTACAGTATGCTTTTCGCCTTTCTCTTTATCGATAA
AATATTTGTGAATATCATTTATTTTCAAGGCATGTTCTATACGCAAATATTTGGTATTCCGGTATTTTTATTCTTAAACA
TCGTTATCATCTTACTTTGTATCATCGTGGGTTCTGTGTTAGCTTATAAGATTAATCAACAGAACCACTGGCTTCAAGAA
CAAATCGAACGTTCGATCGAAGGTGAAACAGTCGGCATTAACGATCAAAATATTGAACTGTATAATGAAACGATCGCGCT
CTATCAAACGTTGGTGCCACTCAATCAAGAAGTACATAAATTACGTATGAAGACTCAGAATTTAACGAATGAATCATATA
ACATCAATGATAAGAAAGTTAAGAAAATCATCGAAGACGAGCGTCAACGTTTAGCACGAGAATTACACGACTCAGTGAGT
CAGCAACTGTTTGCAGCAAGTATGATGTTGTCAGCAATCAAGGAATCAACACTAGAGCCACCGCTCGATCAACAAATACC
CACGTTAGAAAAAATGGTACAAGATTCACAACTTGAAATGAGAGCCTTACTTTTACATCTTAGACCTATCGGATTGAAAG
ATAAATCGCTAGGAGAAGGAATTAAAGATTTAGTTGTTGATCTTCAGAAGAAAGTGCCGATGAAAGTGGTTCACCAAATA
GAAGATTTCAAAGTCCCTAAAGGCATTGAAGATCATTTATTCCGCATTACTCAAGAGGCGATATCAAACACCTTACGTCA
CTCTAACGGAACGAAAGTAACGATTGAATTATTCAATAAAGAAGATTATTTACTACTACGTATACAAGATGACGGTAAAG
GATTTAACGTAGATGATAAAGTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCGCTAGAAATCGGCGCGAAC
TTCCACATTGTATCCTTGCCAGATTCAGGGACACGTATCGAAGTGAAAGCACCGTTGAACAAGGAGGAATTAAGTGATGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A1Z3TZK4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	89.914	100	0.899