Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CEQ33_RS12670 Genome accession   NZ_CP022093
Coordinates   2499665..2500294 (+) Length   209 a.a.
NCBI ID   WP_002482846.1    Uniprot ID   A0A380HJV9
Organism   Staphylococcus saprophyticus strain FDAARGOS_355     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2494665..2505294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CEQ33_RS12645 (CEQ33_12680) - 2495514..2496500 (-) 987 WP_002482841.1 aromatic acid exporter family protein -
  CEQ33_RS12650 (CEQ33_12685) map 2496675..2497427 (+) 753 WP_011302778.1 type I methionyl aminopeptidase -
  CEQ33_RS12655 (CEQ33_12690) - 2497531..2497917 (+) 387 WP_011302779.1 hypothetical protein -
  CEQ33_RS12660 (CEQ33_12695) liaF 2497934..2498635 (+) 702 WP_011302780.1 cell wall-active antibiotics response protein LiaF -
  CEQ33_RS12665 (CEQ33_12700) vraS 2498632..2499675 (+) 1044 WP_011302781.1 sensor histidine kinase Regulator
  CEQ33_RS12670 (CEQ33_12705) vraR 2499665..2500294 (+) 630 WP_002482846.1 response regulator transcription factor Regulator
  CEQ33_RS12675 (CEQ33_12710) - 2500451..2501623 (-) 1173 WP_011302782.1 YihY/virulence factor BrkB family protein -
  CEQ33_RS12680 (CEQ33_12715) - 2502035..2502319 (-) 285 WP_002482848.1 hypothetical protein -
  CEQ33_RS12685 (CEQ33_12720) - 2502326..2502790 (-) 465 WP_011302783.1 low molecular weight protein-tyrosine-phosphatase -
  CEQ33_RS12690 (CEQ33_12725) - 2502925..2503128 (+) 204 WP_002482850.1 DUF1128 family protein -
  CEQ33_RS12695 (CEQ33_12730) - 2503142..2504380 (+) 1239 WP_011302784.1 aminopeptidase -
  CEQ33_RS12700 (CEQ33_12735) - 2504594..2505115 (+) 522 WP_011302785.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23684.19 Da        Isoelectric Point: 4.6997

>NTDB_id=236628 CEQ33_RS12670 WP_002482846.1 2499665..2500294(+) (vraR) [Staphylococcus saprophyticus strain FDAARGOS_355]
MPIKVLFVDDHEMVRIGISSYLSTQSDIDVVGEGKSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQVKKDLPNIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=236628 CEQ33_RS12670 WP_002482846.1 2499665..2500294(+) (vraR) [Staphylococcus saprophyticus strain FDAARGOS_355]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAAATGGTTCGAATAGGTATTTCTAGTTATTTATCCACACAATCAGA
TATAGATGTCGTAGGGGAAGGTAAGTCAGGAAAAGATGCAATCGAAAAAGCACATGAACTGAAACCGGACCTAATTTTAA
TGGATTTACTTATGGACGATATGGATGGTGTCGAAGCAACTGAACAAGTTAAAAAAGACTTGCCAAATATTAAAGTTGTC
ATGCTTACGAGTTATATTGAAGATAACGAAGTCTATCGTGCACTTGATTCCGGTGTAGATAGCTATATATTGAAAACAAC
AAGTGCTAGTGATATTGCTGAAGCGATTCGTAAGACTTACAATAATGAGTCAGTATTTGAAGCAGAAGTCCTAGTTAAAA
TGAGAAATAGGATGAAACAACGAGCTGAATTGTATGAAATGCTCACAGAACGTGAAATGGAGATTTTATTACTGATTGCT
AAAGGTTACTCTAACCAAGAGATTGCCAGCGCTTCACATATTACGATTAAAACAGTGAAAACGCATGTAAGTAATATCCT
AAGTAAATTAGAAGTTCAAGATAGAACTCAAGCCGTCATATATGCATTCCAGCACAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380HJV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.952

100

0.9

Multiple sequence alignment