Detailed information NTG0236627

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CEQ33_RS12665
• Genome accession: NZ_CP022093
• Coordinates: 2498632..2499675 (+)
• Length: 347 a.a.
• NCBI ID: WP_011302781.1
• Uniprot ID: -
• Organism: Staphylococcus saprophyticus strain FDAARGOS_355
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2493632..2504675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CEQ33_RS12635 (CEQ33_13070)	-	2494262..2494567 (+)	306	WP_011302776.1	helix-turn-helix domain-containing protein	-
CEQ33_RS12640 (CEQ33_12675)	-	2494573..2495436 (+)	864	WP_075345165.1	IS3 family transposase	-
CEQ33_RS12645 (CEQ33_12680)	-	2495514..2496500 (-)	987	WP_002482841.1	aromatic acid exporter family protein	-
CEQ33_RS12650 (CEQ33_12685)	map	2496675..2497427 (+)	753	WP_011302778.1	type I methionyl aminopeptidase	-
CEQ33_RS12655 (CEQ33_12690)	-	2497531..2497917 (+)	387	WP_011302779.1	hypothetical protein	-
CEQ33_RS12660 (CEQ33_12695)	liaF	2497934..2498635 (+)	702	WP_011302780.1	cell wall-active antibiotics response protein LiaF	-
CEQ33_RS12665 (CEQ33_12700)	vraS	2498632..2499675 (+)	1044	WP_011302781.1	sensor histidine kinase	Regulator
CEQ33_RS12670 (CEQ33_12705)	vraR	2499665..2500294 (+)	630	WP_002482846.1	response regulator transcription factor	Regulator
CEQ33_RS12675 (CEQ33_12710)	-	2500451..2501623 (-)	1173	WP_011302782.1	YihY/virulence factor BrkB family protein	-
CEQ33_RS12680 (CEQ33_12715)	-	2502035..2502319 (-)	285	WP_002482848.1	hypothetical protein	-
CEQ33_RS12685 (CEQ33_12720)	-	2502326..2502790 (-)	465	WP_011302783.1	low molecular weight protein-tyrosine-phosphatase	-
CEQ33_RS12690 (CEQ33_12725)	-	2502925..2503128 (+)	204	WP_002482850.1	DUF1128 family protein	-
CEQ33_RS12695 (CEQ33_12730)	-	2503142..2504380 (+)	1239	WP_011302784.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40050.55 Da
• Isoelectric Point: 6.4221

>NTDB_id=236627 CEQ33_RS12665 WP_011302781.1 2498632..2499675(+) (vraS) [Staphylococcus saprophyticus strain FDAARGOS_355]
MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=236627 CEQ33_RS12665 WP_011302781.1 2498632..2499675(+) (vraS) [Staphylococcus saprophyticus strain FDAARGOS_355]
ATGAATCACTACTTTAGAGCGATCGGGTCCATGTTGATATTAGTATATAGTACGTTTTTTGCCATATTCTTTATTGATAA
AGTGTTTGTTAATATAATGTATTTTCAAGGTATGTTTTATACTCAAATATTTGGCATACCTGTACTGCTTTTTTTAAATC
TAATGGTGATTTTACTCTGTATTATTGTAGGTTCTGTCTTAGCATATAAAATCAATCAGCAAAATCATTGGTTAAAAGAT
CAAATTGAACGTTCAATAGAAGGTCAAACAGTGGGTATCAATGATCAAAATATTGAATTATACAACGAAACAATCGAACT
ATATCAAACGCTTGTGCCTTTAAATCAAGAAGTACATAAATTAAGAATGAAAACACAGAACCTGACGAATGAATCTTATA
ATATCAATGATGTTAAAGTTAAGAAAATTATAGAAGACGAACGCCAACGTTTAGCGCGTGAATTACATGATTCAGTTAGT
CAACAATTATTCGCAGCAAGTATGATGTTATCAGCAATTAAAGAGACAGAATTGAAGGCCCCATTGGACCAACAAATACC
AGTATTAGAAAAAATGATTCAAGATTCCCAATTAGAAATGAGAGCACTACTATTACACTTAAGACCTATTGGTTTGAAAG
ATAAATCTTTAGGTGAGGGTATTAAAGATTTAGTCGTTGATTTACAGAAAAAAGTACCAATGAAAGTGGTACATGATATT
GAAGAATTCAAAGTACCAAAAGGTATCGAGGACCATTTATTCCGTATTACGCAAGAAGCCATTTCTAATACGCTAAGACA
TTCTAAAGGAACGAAGGTCACAATTGAATTATTTAATAGGGAAGAATATTTGTTATTGCGTATACAAGATAATGGTAAAG
GGTTTAATGTAGATGATAAGGTAGAACAAAGTTATGGATTAAAAAATATGCGCGAACGTGCACTAGAAATAGGTGCAACA
TTTCATATCGTTTCTTTGCCTGATGCAGGTACGAGAATTGAAGTAAAGGCACCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.32	100	0.873