Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C7A05_RS02380 Genome accession   NZ_CP027591
Coordinates   276490..277122 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3011     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 271490..282122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7A05_RS02355 yhfG 271623..271790 (+) 168 WP_000736863.1 YhfG family protein -
  C7A05_RS02360 fic 271780..272382 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  C7A05_RS02365 pabA 272414..272977 (+) 564 WP_000601849.1 aminodeoxychorismate synthase component 2 -
  C7A05_RS02370 argD 273063..274283 (+) 1221 WP_062882667.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C7A05_RS02375 yhfK 274349..276439 (-) 2091 WP_062882666.1 YccS/YhfK family putative transporter -
  C7A05_RS02380 crp 276490..277122 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C7A05_RS02390 yhfA 277424..277828 (+) 405 WP_001148908.1 OsmC family protein -
  C7A05_RS02395 prkB 277883..278752 (-) 870 WP_062882665.1 phosphoribulokinase -
  C7A05_RS02400 yheU 278806..279024 (-) 219 WP_000907085.1 YheU family protein -
  C7A05_RS02405 yheT 279018..280040 (-) 1023 WP_000057379.1 hydrolase -
  C7A05_RS02410 yheS 280040..281953 (-) 1914 WP_000634790.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=236447 C7A05_RS02380 WP_000242755.1 276490..277122(-) (crp) [Escherichia coli strain 2014C-3011]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=236447 C7A05_RS02380 WP_000242755.1 276490..277122(-) (crp) [Escherichia coli strain 2014C-3011]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment