Detailed information NTG0023556

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BJE04_RS03675
• Genome accession: NC_005139
• Coordinates: 714179..716752 (+)
• Length: 857 a.a.
• NCBI ID: WP_011149573.1
• Uniprot ID: Q7MNK1
• Organism: Vibrio vulnificus YJ016
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 709179..721752

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJE04_RS03650 (VV0710)	hpf	709384..709707 (-)	324	WP_011078575.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
BJE04_RS03655 (VV0711)	-	710041..711378 (-)	1338	WP_011149570.1	IS4-like element ISVvu3 family transposase	-
BJE04_RS03660 (VV0712)	comL	711502..712227 (-)	726	WP_011078574.1	outer membrane protein assembly factor BamD	Machinery gene
BJE04_RS03665 (VV0713)	rluD	712364..713341 (+)	978	WP_011149571.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
BJE04_RS03670 (VV0714)	pgeF	713345..714061 (+)	717	WP_181392316.1	peptidoglycan editing factor PgeF	-
BJE04_RS03675 (VV0715)	clpC	714179..716752 (+)	2574	WP_011149573.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 96096.99 Da
• Isoelectric Point: 5.2933

>NTDB_id=23556 BJE04_RS03675 WP_011149573.1 714179..716752(+) (clpC) [Vibrio vulnificus YJ016]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTILNVDVTHLRSKLSEMLDRLPKVSGIGGD
VQLSSAMGAMFNLCDKIAQKRQDAYISSEIFLLAAIEDRGPLGQLFKELGLTEQKVSQAIEQIRGGQKVNDQNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIINNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELSKEEGNIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHHVEITDPAIVAAASLSHRYVSDRQLPDKAIDLIDEAASS
IRMQIDSKPEALDKLERKIIQLKIEQQALSNEHDEASEKRLRSLNEELNEKEREFAELEEIWNAEKAALSGTQHIKAALE
QARMDMEFARRAGDLSRMSELQYGRIPELEKQLDLATQAEMQEMTLLKNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEEVLHKRVIGQKEAVEVVANAIRRSRAGLSDPNKPIGSFLFLGPTGVGKTELCKTLANFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFAMLDYQGIKEQVMEVVTKHFRPEFLNRVDETVVFHPLSQDHIKSIAAIQLNRLANRMEEHGYQLEVSDKAL
ELIAQVGFDPVYGARPLKRAIQQSIENPLAKSILAGSVLPDKKIQLIVNNDQIVAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=23556 BJE04_RS03675 WP_011149573.1 714179..716752(+) (clpC) [Vibrio vulnificus YJ016]
ATGCGTCTTGATCGATTTACCAGCAAATTTCAAATCGCTATCTCTGATGCACAATCATTGGCGTTAGGGCGCGATCATCA
ATACATTGAACCTGTTCACTTAATGGTGGCGCTGCTTGATCAAAACGGCAGCCCTATTCGTCCACTGCTGACCATCTTAA
ATGTGGATGTCACTCACCTACGTTCAAAACTCAGCGAAATGTTGGATCGCTTACCCAAAGTGAGCGGTATTGGTGGTGAT
GTACAGCTTTCCTCAGCCATGGGCGCGATGTTTAACTTGTGCGATAAGATTGCACAAAAACGCCAAGATGCTTACATCTC
ATCTGAAATCTTTTTGCTCGCAGCCATCGAAGATAGAGGACCACTTGGCCAGCTCTTCAAAGAACTTGGCTTAACTGAAC
AGAAAGTGAGTCAAGCTATCGAGCAAATTCGCGGTGGTCAAAAAGTGAATGATCAAAATGCGGAAGAACTTCGCCAAGCG
TTAGAGAAATTTACCATTGATCTGACGGAACGTGCAGAACAGGGCAAACTTGACCCTGTGATTGGACGTGACGATGAAAT
TCGTCGCACCATCCAAGTATTGCAGCGTCGAACCAAAAACAACCCCGTGATCATTGGTGAGCCAGGTGTTGGTAAAACCG
CCATTGTTGAAGGTTTAGCACAACGTATCATCAATAACGAGGTGCCCGAAGGTCTGCGTGGTCGCCGAGTGTTGTCACTC
GATATGGGCGCGTTGGTGGCTGGAGCGAAGTACCGTGGTGAGTTTGAAGAGCGACTTAAATCGGTATTGAATGAGTTGTC
TAAAGAAGAAGGCAATATCATCCTCTTTATTGATGAGCTTCATACCATGGTTGGCGCCGGTAAAGGTGAAGGTTCGATGG
ATGCGGGCAATATGCTCAAACCCGCATTGGCACGTGGTGAGTTACATTGTGTGGGCGCAACGACACTTGACGAGTATCGT
CAGTATATCGAGAAAGATCCGGCACTTGAGCGCCGCTTCCAAAAAGTGCTGGTTGATGAACCAACAGTGGAAGACACCAT
TGCAATTTTGCGTGGTTTAAAAGAGCGCTATGAGCTGCATCATCATGTTGAAATTACCGATCCAGCGATCGTTGCTGCGG
CCAGTTTGTCGCATCGCTATGTTTCTGATCGTCAATTACCGGATAAAGCGATCGACCTTATCGACGAAGCCGCATCCAGT
ATTCGCATGCAGATCGATTCTAAACCCGAAGCTCTGGATAAGTTGGAGCGCAAAATCATCCAACTTAAGATAGAGCAACA
GGCGCTGAGTAATGAACACGATGAAGCGAGTGAAAAACGTCTGCGCTCACTTAACGAAGAGTTGAATGAGAAAGAGCGTG
AGTTTGCTGAGTTAGAGGAAATTTGGAACGCAGAAAAAGCCGCGCTGTCTGGCACTCAGCACATTAAAGCGGCGTTAGAG
CAAGCACGCATGGATATGGAGTTTGCGAGACGAGCGGGGGATCTTAGCCGCATGTCTGAGCTTCAATATGGCCGTATTCC
AGAGCTTGAGAAGCAACTTGACCTAGCAACGCAAGCAGAAATGCAGGAAATGACCTTGTTGAAAAACAAAGTCACCGATA
ATGAAATTGCAGAAGTGCTTTCTAAGCAAACGGGTATCCCTGTCTCCAAAATGCTTGAAGCAGAAAAAGAAAAACTGCTT
CGCATGGAAGAGGTGCTGCATAAACGTGTTATTGGGCAGAAAGAGGCGGTGGAAGTTGTTGCGAATGCGATACGTCGCAG
CCGGGCGGGCTTGTCCGATCCCAATAAACCGATTGGTTCGTTCTTATTCTTAGGTCCAACCGGTGTGGGGAAAACGGAAC
TGTGCAAAACGTTGGCGAATTTCATGTTCGACAGTGAAGATGCCATGGTGCGTATCGACATGTCTGAGTTTATGGAGAAA
CACTCAGTGGCACGCTTAGTCGGTGCACCTCCGGGCTATGTGGGTTATGAAGAAGGTGGATATTTAACGGAAGCGGTTCG
ACGTAAGCCTTATTCAGTGATTTTGCTCGATGAAGTGGAAAAGGCACACCCTGATGTGTTCAACATCCTGCTACAAGTCT
TGGATGACGGTCGATTGACGGATGGACAAGGTAGAACAGTGGATTTCCGCAATACCGTGGTCATCATGACATCAAACCTA
GGCTCAAGCCGCATCCAAGAAAACTTCGCTATGTTGGATTACCAAGGTATCAAAGAACAGGTGATGGAAGTGGTGACCAA
ACACTTCAGGCCGGAGTTTTTGAACCGTGTTGATGAGACAGTGGTCTTCCACCCACTTAGTCAAGATCATATTAAGTCGA
TCGCAGCGATTCAACTTAACCGCTTGGCGAATCGCATGGAAGAGCATGGCTATCAGTTGGAAGTGTCCGATAAAGCGCTC
GAATTGATCGCACAAGTTGGTTTTGACCCGGTTTACGGAGCAAGACCATTGAAACGAGCGATTCAGCAAAGTATCGAGAA
CCCACTGGCGAAATCTATTTTGGCGGGCTCGGTGCTACCGGATAAGAAAATACAGCTTATCGTCAACAACGACCAAATTG
TGGCACACCAATAG

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• AAA lid domain (AAA_lid_9) (342-444)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-335)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

3D structure

• AlphaFold DB: Q7MNK1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.828	100	0.474
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.54	100	0.415
clpE	Streptococcus mutans UA159	48.306	79.23	0.383
clpE	Streptococcus pneumoniae D39	48.301	78.996	0.382
clpE	Streptococcus pneumoniae Rx1	48.301	78.996	0.382
clpE	Streptococcus pneumoniae R6	48.301	78.996	0.382
clpC	Lactococcus lactis subsp. cremoris KW2	46.154	80.397	0.371