Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   CD795_RS08285 Genome accession   NZ_CP021907
Coordinates   1657211..1657897 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain Seattle 1945 isolate G478     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1652211..1662897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CD795_RS08265 rpsT 1653125..1653376 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  CD795_RS08270 holA 1653421..1654395 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  CD795_RS08275 comEC 1654452..1656653 (-) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CD795_RS08280 - 1656658..1657119 (-) 462 WP_000439692.1 ComE operon protein 2 -
  CD795_RS08285 comEA 1657211..1657897 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  CD795_RS08290 - 1657937..1658653 (-) 717 WP_000084835.1 class I SAM-dependent DNA methyltransferase -
  CD795_RS08295 rsfS 1658656..1659009 (-) 354 WP_001088020.1 ribosome silencing factor -
  CD795_RS08300 yqeK 1659010..1659594 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  CD795_RS08305 nadD 1659584..1660153 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  CD795_RS08310 yhbY 1660156..1660446 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  CD795_RS08315 aroE 1660450..1661256 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  CD795_RS08320 yqeH 1661270..1662370 (-) 1101 WP_001280132.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=234726 CD795_RS08285 WP_001794049.1 1657211..1657897(-) (comEA) [Staphylococcus aureus strain Seattle 1945 isolate G478]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=234726 CD795_RS08285 WP_001794049.1 1657211..1657897(-) (comEA) [Staphylococcus aureus strain Seattle 1945 isolate G478]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952

Multiple sequence alignment