Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   CDH84_RS05565 Genome accession   NZ_CP021771
Coordinates   1088333..1089559 (-) Length   408 a.a.
NCBI ID   WP_000918412.1    Uniprot ID   A0AAV3JKF5
Organism   Streptococcus agalactiae strain B507     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1058846..1100107 1088333..1089559 within 0


Gene organization within MGE regions


Location: 1058846..1100107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CDH84_RS05400 (CDH84_05350) - 1060565..1063012 (-) 2448 WP_000331160.1 ATP-binding protein -
  CDH84_RS05405 (CDH84_05355) - 1062996..1063388 (-) 393 WP_000723888.1 conjugal transfer protein -
  CDH84_RS05410 (CDH84_05360) - 1063477..1063974 (-) 498 WP_000342539.1 antirestriction protein ArdA -
  CDH84_RS05415 (CDH84_05365) - 1064091..1064312 (-) 222 WP_001009056.1 hypothetical protein -
  CDH84_RS05420 (CDH84_05370) mobT 1064355..1065560 (-) 1206 WP_000398284.1 MobT family relaxase -
  CDH84_RS05425 (CDH84_05375) - 1065583..1065735 (-) 153 WP_000879507.1 hypothetical protein -
  CDH84_RS05430 (CDH84_05380) - 1065738..1067123 (-) 1386 WP_000813488.1 FtsK/SpoIIIE domain-containing protein -
  CDH84_RS05435 (CDH84_05385) - 1067152..1067538 (-) 387 WP_000985015.1 YdcP family protein -
  CDH84_RS05440 (CDH84_05390) - 1067554..1067868 (-) 315 WP_000420682.1 YdcP family protein -
  CDH84_RS05450 (CDH84_05400) - 1068266..1069501 (+) 1236 WP_000248019.1 AbiH family protein -
  CDH84_RS05455 (CDH84_05405) - 1069703..1070884 (-) 1182 WP_001284550.1 site-specific integrase -
  CDH84_RS05460 (CDH84_05410) - 1070902..1071135 (-) 234 WP_000198709.1 DUF3173 family protein -
  CDH84_RS05465 (CDH84_05415) - 1071139..1071705 (-) 567 WP_000031192.1 replication protein -
  CDH84_RS11195 - 1071840..1072453 (-) 614 Protein_1023 hypothetical protein -
  CDH84_RS11305 - 1072455..1073531 (-) 1077 Protein_1024 ATP-binding cassette domain-containing protein -
  CDH84_RS05490 (CDH84_05440) - 1073531..1073845 (-) 315 WP_000857661.1 hypothetical protein -
  CDH84_RS05495 (CDH84_05445) - 1074080..1075285 (-) 1206 WP_000884910.1 hypothetical protein -
  CDH84_RS05500 (CDH84_05450) - 1075337..1075828 (-) 492 WP_001129984.1 hypothetical protein -
  CDH84_RS05505 (CDH84_05455) - 1075842..1079453 (-) 3612 WP_000974945.1 TaqI-like C-terminal specificity domain-containing protein -
  CDH84_RS05510 (CDH84_05460) rplL 1079694..1080059 (-) 366 WP_001196976.1 50S ribosomal protein L7/L12 -
  CDH84_RS05515 (CDH84_05465) rplJ 1080123..1080623 (-) 501 WP_001287285.1 50S ribosomal protein L10 -
  CDH84_RS05520 (CDH84_05470) - 1081057..1083165 (+) 2109 WP_000002804.1 ATP-dependent Clp protease ATP-binding subunit -
  CDH84_RS05530 (CDH84_05475) mmuM 1083259..1084202 (-) 944 Protein_1032 homocysteine S-methyltransferase -
  CDH84_RS05535 (CDH84_05480) - 1084207..1085583 (-) 1377 Protein_1033 amino acid permease -
  CDH84_RS05540 (CDH84_05485) - 1085713..1086363 (-) 651 WP_000120090.1 HXXEE domain-containing protein -
  CDH84_RS11200 - 1086521..1086844 (-) 324 WP_001867206.1 HXXEE domain-containing protein -
  CDH84_RS05555 (CDH84_05500) - 1087116..1087745 (+) 630 WP_000140673.1 TetR/AcrR family transcriptional regulator -
  CDH84_RS05560 (CDH84_05505) yihA 1087726..1088322 (-) 597 WP_000796925.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  CDH84_RS05565 (CDH84_05510) clpX 1088333..1089559 (-) 1227 WP_000918412.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  CDH84_RS05575 (CDH84_05520) - 1089777..1090271 (-) 495 WP_000166043.1 dihydrofolate reductase -
  CDH84_RS05580 (CDH84_05525) - 1090351..1091190 (-) 840 WP_000158597.1 thymidylate synthase -
  CDH84_RS05585 (CDH84_05530) - 1091344..1092516 (+) 1173 WP_001873466.1 hydroxymethylglutaryl-CoA synthase -
  CDH84_RS05590 (CDH84_05535) - 1092518..1093801 (+) 1284 WP_000161688.1 hydroxymethylglutaryl-CoA reductase, degradative -
  CDH84_RS05595 (CDH84_05540) - 1093893..1094342 (+) 450 WP_001039193.1 DUF1836 domain-containing protein -
  CDH84_RS05600 (CDH84_05545) - 1094335..1094991 (+) 657 WP_000910679.1 hemolysin III family protein -
  CDH84_RS05605 (CDH84_05550) - 1095078..1095992 (+) 915 WP_000833762.1 diacylglycerol kinase family protein -
  CDH84_RS05610 (CDH84_05555) - 1096093..1096947 (+) 855 WP_000206685.1 glutathione S-transferase C-terminal domain-containing protein -
  CDH84_RS05615 (CDH84_05560) - 1096993..1097211 (-) 219 WP_000594205.1 DUF4649 family protein -
  CDH84_RS05620 (CDH84_05565) fni 1097279..1098274 (-) 996 WP_000184894.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  CDH84_RS05625 (CDH84_05570) - 1098271..1099263 (-) 993 WP_000241520.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44850.28 Da        Isoelectric Point: 4.4424

>NTDB_id=233259 CDH84_RS05565 WP_000918412.1 1088333..1089559(-) (clpX) [Streptococcus agalactiae strain B507]
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKN
ILFIVGGAFDGIEDLVKQRLGEKIIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGT
DKPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=233259 CDH84_RS05565 WP_000918412.1 1088333..1089559(-) (clpX) [Streptococcus agalactiae strain B507]
ATGGCTGGGAATCGTAATAACGATATGAATGTCTATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAATGGTGTTTTCATTTGTAATGAATGTGTGGCCTTATCACAAGAAATTATTAAGGAAGAATTAGCTGAGGAAG
TACTTGCTGATTTAGCAGAAGTACCAAAACCTAAGGAACTATTAGAAATATTAAATCAATATGTTGTAGGGCAAGATCGT
GCTAAACGTGCTTTAGCAGTTGCTGTCTACAATCATTACAAGCGTGTTAGTTATACCGAGAGTAGTGACGATGATGTAGA
TTTGCAAAAATCCAACATTTTGATGATTGGTCCAACTGGCTCAGGAAAAACCTTCTTAGCACAAACACTAGCTAAAAGCC
TTAATGTACCGTTTGCTATTGCAGATGCGACTTCATTGACCGAAGCAGGATACGTTGGAGAAGATGTTGAGAATATTCTT
CTTAAATTGATTCAAGCTGCTGATTATAATGTCGAACGTGCTGAGCGTGGTATTATCTACGTTGATGAAATAGATAAAAT
TGCTAAGAAAGGCGAAAATGTTTCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTATTG
AGGGTACGGTAGCAAGTGTTCCCCCACAGGGTGGGCGTAAACATCCTAACCAAGAAATGATTCAAATTAATACCAAGAAC
ATCCTTTTTATTGTCGGTGGTGCTTTTGATGGTATTGAAGACCTTGTGAAGCAACGTTTAGGCGAAAAAATTATTGGTTT
TGGACAGACAAGCCGCAAAATTGATGACAACGCTTCTTATATGCAAGAGATAATTTCTGAGGATATTCAAAAGTTTGGAC
TGATTCCAGAGTTTATTGGCCGTTTACCAGTAGTTGCAGCGTTAGAACTTCTTACTGCAGAAGATCTGGTTCGTATTCTG
ACAGAACCACGCAATGCTTTGGTTAAACAATACCAAACCTTATTATCTTATGATGGTGTAGAATTGGAATTTGATCAGGA
TGCTCTATTGGCTATCGCTGATAAGGCTATCGAGCGCAAGACTGGTGCACGTGGTTTACGTTCTATTATTGAAGAAACGA
TGCTTGATATCATGTTTGAAATTCCAAGCCAAGAAGATGTAACAAAAGTTCGTATCACAAAGGCTGCTGTTGAGGGTACT
GACAAGCCTGTTTTAGAGACGGCTTAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

90.709

100

0.909
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58

98.039

0.569

Multiple sequence alignment