Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CCD88_RS10350 Genome accession   NZ_CP021724
Coordinates   1840957..1844115 (-) Length   1052 a.a.
NCBI ID   WP_149449394.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 12-330     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1835957..1849115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCD88_RS10335 (CCD88_10500) yccS 1836727..1838877 (+) 2151 WP_002224737.1 YccS family putative transporter -
  CCD88_RS10345 (CCD88_10520) - 1840298..1840582 (-) 285 WP_002216166.1 GIY-YIG nuclease family protein -
  CCD88_RS10350 (CCD88_10525) pilC 1840957..1844115 (-) 3159 WP_149449394.1 PilC family type IV pilus tip adhesin Machinery gene
  CCD88_RS12545 - 1844080..1844238 (+) 159 WP_153310287.1 hypothetical protein -
  CCD88_RS10355 (CCD88_10535) pilA 1844775..1846040 (-) 1266 WP_002228837.1 signal recognition particle-docking protein FtsY Machinery gene
  CCD88_RS10360 (CCD88_10545) msrAB 1846186..1847754 (+) 1569 WP_002216163.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  CCD88_RS10365 (CCD88_10550) - 1847856..1848341 (-) 486 WP_002221794.1 CinA family protein -

Sequence

Protein


Download         Length: 1052 a.a.        Molecular weight: 115496.17 Da        Isoelectric Point: 9.5445

>NTDB_id=232833 CCD88_RS10350 WP_149449394.1 1840957..1844115(-) (pilC) [Neisseria meningitidis strain 12-330]
MNKTWKRQVFRHTALYTAILMFSHTGGGGGQAQTQTHKYAIVMNNQKLPEVKWGNDYSSLTDKSNEREVTHTSKFVVAKK
HISFSFNNTDEVVAEKKDAVVFGAATYLPPYGKVSGFDTAKLAERKNALDQIGTTHPGLIGYNYQDVTCASGNCPELSYR
TQFTFNNGLKRNGNGGRLDIYEDKSRDSSPIYKLKDYPWLGVSFNLGGESSFKPKRQGSLVSSFSEDVTQQNGTQDQYKS
KNLVYTTDDYNSKGNKNHQDKHHAVAFYLNAKLHLLDKKQIKNIAQGVTVDLGTLKTRIEPTDAWKNRQGSYFNNGTWTY
EEKGSVSVKLKLPEVKAGRCITTPNPNPKSKAPSPALTAPALWFGAGQDGKAEMYSASVSTYPDSSSSRIYLQNLKRKTD
SNRPGRYSLADLSASDIQSKEPTFTSRQTIIRLDGGVRHIQLDRNNEVTSFNGDNGTFGIVNEGSVVPESNEWKKVLLPW
TVRGFADDSKFKAFNKEKNNDNKPKYSQRYRIRENGNNGKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKKGNGGDARD
YSLKLSYIPGTMPRKDIQSQDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVNNLNGQDRVFMFGAMGFGGRGAYALDLT
KADGNDPTKASLFDVKDNGNNGNNRVELGYTVGTPQIGKTHNGKYAAFLASGYATKEITSGENKTALYVYDLENNNGTPI
AKIEVPNGKGGLSSPTLVDKDLDGTIDIAYAGDRGGKMYRFDLSSQSPDQWTVRPIFEGTKPITSAPAISQLKDKRVVIF
GTGSDLSEDDVDKMDEQYIYGIFDDDTETTGNVKVDLKGLGGGLLEQHLTQEDKTLFLTDYKRSDGSGNKGWVVKLKDGQ
RVTVKPTVVLRTAFVTIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPDANTKVAQYSGDKKTSSGKSIPIGCMQ
KGNEIVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTC
GMKRISWREVFF

Nucleotide


Download         Length: 3159 bp        

>NTDB_id=232833 CCD88_RS10350 WP_149449394.1 1840957..1844115(-) (pilC) [Neisseria meningitidis strain 12-330]
ATGAATAAAACTTGGAAACGGCAGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAAGCGCAAACGCAAACGCATAAATACGCTATTGTAATGAACAATCAAAAGCTGCCTGAGGTAAAGTGGG
GGAACGACTATAGCTCATTGACGGACAAAAGCAATGAACGCGAAGTTACCCATACGAGTAAATTTGTTGTAGCAAAAAAG
CACATTAGTTTCTCATTCAATAATACCGATGAAGTTGTTGCTGAAAAAAAAGATGCTGTCGTTTTCGGCGCGGCGACTTA
TCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGCTAAGCTGGCCGAGCGCAAAAATGCCCTTGATCAGATTGGTA
CGACCCACCCTGGGTTGATAGGCTACAACTACCAAGATGTCACTTGCGCCAGCGGAAACTGTCCTGAACTTAGCTATAGA
ACCCAATTTACCTTCAATAACGGGTTGAAAAGAAATGGAAACGGCGGCAGGCTGGATATATACGAAGACAAAAGCCGCGA
CAGTTCGCCCATTTACAAATTGAAGGATTATCCTTGGTTGGGCGTGTCTTTCAATTTGGGCGGCGAGAGCTCCTTCAAAC
CAAAGAGACAAGGTTCTTTGGTATCTTCTTTTAGCGAGGATGTGACGCAGCAAAATGGTACACAAGACCAATACAAAAGC
AAAAACCTCGTTTATACGACAGACGATTACAATAGTAAGGGTAATAAAAACCATCAGGACAAACACCACGCCGTCGCCTT
TTATCTGAACGCCAAGCTGCATTTGCTGGATAAAAAACAAATCAAAAATATCGCGCAAGGCGTAACAGTTGATTTGGGTA
CCTTGAAAACACGCATCGAGCCGACGGACGCGTGGAAAAACAGGCAGGGGAGCTATTTTAATAATGGTACTTGGACGTAT
GAAGAGAAAGGATCAGTCAGCGTCAAACTCAAATTGCCGGAAGTCAAAGCAGGCCGCTGCATCACCACACCGAACCCCAA
TCCCAAATCCAAAGCCCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGGAGCTGGGCAAGATGGTAAGGCGGAGA
TGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTACCTTCAAAATCTGAAAAGAAAAACCGAC
TCCAACAGACCCGGCCGCTATTCCCTCGCAGACTTGAGTGCGTCGGATATTCAAAGTAAAGAGCCGACTTTCACAAGTCG
GCAAACAATCATCCGCTTGGATGGTGGCGTACGGCATATCCAACTGGATAGAAACAATGAGGTCACTAGTTTTAATGGCG
ACAACGGAACTTTCGGCATTGTTAATGAAGGGAGCGTCGTTCCTGAAAGCAACGAGTGGAAAAAAGTGCTGCTGCCTTGG
ACGGTTCGGGGTTTTGCTGATGACAGTAAATTTAAAGCATTCAACAAAGAAAAAAACAACGACAACAAGCCAAAATACAG
CCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAAGCGCGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGG
TCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAAAAAGGCAACGGCGGGGACGCGCGCGAC
TATAGTCTGAAGCTCAGCTACATCCCGGGCACGATGCCGCGCAAGGATATTCAAAGTCAAGACTCCACCCTCGCCAAAGA
GCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCAAGTTAACA
ACTTAAATGGGCAAGACCGCGTGTTTATGTTCGGCGCGATGGGCTTTGGCGGCAGAGGTGCGTATGCCTTGGATTTGACC
AAAGCCGACGGCAATGACCCGACAAAAGCCTCTTTGTTTGATGTAAAAGATAATGGCAATAACGGCAATAATCGCGTGGA
ATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATG
CGACTAAAGAAATTACCAGCGGCGAGAATAAAACCGCGCTGTATGTGTATGATTTGGAAAACAACAACGGTACGCCGATT
GCAAAAATCGAAGTACCCAACGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACAATCGA
TATCGCCTATGCCGGCGATCGCGGCGGGAAAATGTACCGCTTTGATTTGAGCAGTCAAAGTCCTGATCAATGGACTGTAC
GCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTCATCTTC
GGCACGGGCAGCGATTTGAGTGAGGATGATGTTGATAAAATGGACGAACAATATATTTACGGTATCTTCGACGACGATAC
GGAGACGACGGGTAATGTAAAGGTAGACCTTAAAGGTTTGGGAGGCGGGCTGCTCGAGCAACACCTTACTCAGGAAGATA
AAACCTTATTCCTGACCGATTATAAGCGATCCGACGGCTCGGGCAATAAGGGCTGGGTAGTGAAATTGAAGGACGGACAG
CGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCATAAATATACGGGTAATGACAAATGCGG
CGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGG
ACGCCAATACGAAGGTCGCGCAATATTCCGGCGATAAGAAAACTTCCAGCGGCAAATCCATCCCTATAGGTTGTATGCAA
AAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAAC
AGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTCCGGCAAAAACA
ACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGC
GGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(523-859)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

74.178

100

0.751

Multiple sequence alignment