Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   C6N65_RS22440 Genome accession   NZ_CP027325
Coordinates   4172377..4173033 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 2013C-4830     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4167377..4178033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6N65_RS22405 - 4168341..4168481 (+) 141 WP_000078920.1 Hok/Gef family protein -
  C6N65_RS28720 - 4168670..4168951 (-) 282 WP_001303543.1 hypothetical protein -
  C6N65_RS22430 pgsA 4169943..4170491 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  C6N65_RS22435 uvrC 4170548..4172380 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  C6N65_RS22440 letA 4172377..4173033 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  C6N65_RS29715 - 4173175..4173246 (+) 72 Protein_4137 transcriptional regulator -
  C6N65_RS28725 yecU 4173328..4173504 (+) 177 Protein_4138 protein YecU -
  C6N65_RS22445 yecF 4173491..4173715 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  C6N65_RS22450 sdiA 4173782..4174504 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  C6N65_RS22455 tcyN 4174734..4175486 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  C6N65_RS22460 tcyL 4175483..4176151 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  C6N65_RS22465 dcyD 4176166..4177152 (-) 987 WP_032206899.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=232171 C6N65_RS22440 WP_000611335.1 4172377..4173033(-) (letA) [Escherichia coli strain 2013C-4830]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=232171 C6N65_RS22440 WP_000611335.1 4172377..4173033(-) (letA) [Escherichia coli strain 2013C-4830]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486