Detailed information NTG0023215

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VV1_RS02345
• Genome accession: NC_004459
• Coordinates: 477717..480290 (-)
• Length: 857 a.a.
• NCBI ID: WP_011078571.1
• Uniprot ID: Q8DEV2
• Organism: Vibrio vulnificus CMCP6
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 472717..485290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VV1_RS02345 (VV1_0482)	clpC	477717..480290 (-)	2574	WP_011078571.1	ATP-dependent chaperone ClpB	Regulator
VV1_RS02350 (VV1_0483)	pgeF	480407..481123 (-)	717	WP_011078572.1	peptidoglycan editing factor PgeF	-
VV1_RS02355 (VV1_0484)	rluD	481127..482104 (-)	978	WP_011078573.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
VV1_RS02360 (VV1_0485)	comL	482241..482966 (+)	726	WP_011078574.1	outer membrane protein assembly factor BamD	Machinery gene
VV1_RS02365 (VV1_0486)	raiA	483319..483642 (+)	324	WP_011078575.1	ribosome-associated translation inhibitor RaiA	-
VV1_RS02370 (VV1_0487)	pheA	483886..485064 (+)	1179	WP_011078576.1	prephenate dehydratase	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 96035.95 Da
• Isoelectric Point: 5.2933

>NTDB_id=23215 VV1_RS02345 WP_011078571.1 477717..480290(-) (clpC) [Vibrio vulnificus CMCP6]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTILNVDVTHLRSKLSEMLDRLPKVSGIGGD
VQLSSAMGAMFNLCDKIAQKRQDAYISSEIFLLAAIEDRGPLGQLFKELGLTEQKVSQAIEQIRGGQKVNDQNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIINNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELSKEEGNIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHHVEITDPAIVAAASLSHRYVSDRQLPDKAIDLIDEAASS
IRMQIDSKPEALDKLERKIIQLKIEQQALSNEHDEASEKRLRSLNEELNEKEREFAELEEIWNAEKAALSGTQHIKAALE
QARMDMEFARRAGDLSRMSELQYGRIPELEKQLDLATQAEMQEMTLLKNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEEVLHKRVIGQKEAVEVVANAIRRSRAGLSDPNKPIGSFLFLGPTGVGKTELCKTLANFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFAMLDYQGIKEQVMEVVTKHFRPEFLNRVDETVVFHPLGQDHIKSIAAIQLNRLANRMEEHGYPLEVSDKAL
ELIAQVGFDPVYGARPLKRAIQQSIENPLAKSILAGSVLPDKKIQLIVNNDQIVAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=23215 VV1_RS02345 WP_011078571.1 477717..480290(-) (clpC) [Vibrio vulnificus CMCP6]
ATGCGTCTTGATCGATTTACCAGCAAATTTCAAATCGCTATCTCTGATGCACAATCATTGGCGTTAGGGCGCGATCATCA
ATACATTGAACCTGTTCACTTAATGGTGGCGCTGCTTGATCAAAACGGCAGCCCTATTCGTCCACTGCTGACCATCTTAA
ATGTGGATGTCACTCACCTACGTTCAAAACTCAGCGAAATGCTGGATCGTTTGCCCAAAGTGAGCGGTATTGGTGGTGAT
GTACAGCTCTCCTCAGCCATGGGCGCGATGTTTAACTTGTGCGATAAGATTGCACAAAAACGCCAAGATGCTTACATCTC
ATCTGAAATCTTTTTGCTCGCAGCAATCGAAGATAGAGGACCACTTGGCCAGCTCTTCAAAGAACTTGGCTTAACTGAAC
AGAAAGTGAGTCAAGCTATCGAGCAAATTCGCGGTGGTCAAAAAGTGAATGATCAAAATGCGGAAGAACTTCGCCAAGCG
TTAGAGAAATTTACCATTGATCTGACGGAACGTGCAGAACAGGGCAAACTTGACCCTGTGATTGGACGTGACGATGAAAT
TCGTCGCACCATCCAAGTATTGCAGCGTCGAACCAAAAACAACCCCGTGATCATTGGTGAGCCAGGTGTTGGTAAAACCG
CCATTGTTGAAGGTTTAGCACAACGTATCATCAATAACGAGGTGCCCGAAGGTCTGCGTGGTCGCCGAGTATTGTCACTC
GATATGGGCGCGTTGGTGGCTGGAGCGAAGTACCGTGGTGAATTTGAAGAGCGACTTAAATCGGTATTGAATGAGTTGTC
TAAAGAAGAAGGCAATATCATCCTCTTTATTGATGAGCTTCATACCATGGTTGGCGCCGGTAAAGGTGAAGGGTCGATGG
ATGCGGGCAATATGCTCAAACCCGCATTGGCACGTGGTGAGTTACATTGTGTGGGCGCAACGACACTTGATGAGTATCGT
CAGTATATCGAGAAAGATCCGGCACTTGAGCGCCGCTTCCAAAAAGTGCTGGTTGATGAACCAACAGTGGAAGACACCAT
TGCAATTTTGCGTGGTTTAAAAGAACGCTATGAGCTGCATCATCATGTTGAAATTACCGATCCAGCGATCGTTGCTGCGG
CCAGTTTGTCGCATCGCTATGTTTCTGATCGTCAATTACCGGACAAAGCGATCGACCTCATCGACGAAGCCGCATCCAGT
ATTCGCATGCAGATCGATTCTAAACCCGAAGCTTTGGATAAGTTGGAGCGCAAAATCATCCAACTTAAGATAGAGCAGCA
GGCGCTGAGTAATGAACACGATGAAGCGAGTGAAAAACGTCTGCGCTCACTTAACGAAGAGTTGAATGAGAAAGAGCGTG
AGTTTGCTGAGTTAGAGGAAATTTGGAATGCGGAAAAAGCCGCGCTGTCTGGCACTCAGCATATTAAAGCGGCGTTAGAG
CAAGCACGCATGGATATGGAGTTTGCAAGACGAGCGGGGGATCTTAGCCGCATGTCTGAGCTTCAATATGGCCGTATTCC
AGAGCTTGAGAAGCAACTTGACCTAGCAACGCAAGCAGAAATGCAGGAAATGACCTTGTTGAAAAACAAAGTCACCGATA
ATGAAATTGCGGAAGTGCTTTCCAAGCAAACGGGTATCCCTGTTTCCAAAATGCTTGAAGCAGAAAAAGAAAAACTACTT
CGCATGGAAGAGGTGCTGCATAAACGCGTTATTGGGCAGAAAGAGGCGGTGGAAGTTGTTGCGAATGCAATACGTCGCAG
CCGCGCGGGTTTGTCCGATCCCAATAAGCCGATTGGTTCGTTCTTATTCTTAGGTCCAACCGGTGTGGGGAAAACGGAAC
TGTGCAAAACGTTGGCGAATTTCATGTTCGACAGTGAAGATGCCATGGTGCGTATCGACATGTCCGAGTTTATGGAGAAA
CACTCAGTGGCACGCTTAGTCGGTGCACCTCCTGGCTATGTGGGTTATGAAGAAGGTGGTTACTTAACGGAAGCCGTTCG
ACGTAAGCCTTATTCAGTGATTTTGCTCGACGAGGTGGAAAAGGCGCATCCTGATGTGTTCAACATCCTGCTGCAAGTCT
TGGATGATGGTCGATTGACGGATGGACAAGGTAGAACAGTGGATTTCCGCAATACCGTGGTCATCATGACATCAAACCTA
GGCTCCAGCCGCATCCAAGAAAACTTCGCTATGTTGGATTACCAAGGCATCAAAGAACAGGTGATGGAAGTGGTGACCAA
GCACTTCAGGCCGGAGTTTTTGAACCGTGTTGATGAGACAGTGGTCTTCCACCCACTTGGTCAAGACCATATTAAGTCGA
TCGCAGCGATTCAACTTAACCGCTTGGCGAATCGCATGGAAGAGCATGGCTATCCGTTGGAAGTGTCTGATAAAGCGCTC
GAATTGATCGCACAAGTTGGTTTTGACCCGGTTTACGGAGCAAGACCATTGAAACGAGCGATTCAGCAAAGTATCGAAAA
CCCGCTGGCGAAATCTATTTTGGCAGGTTCAGTGCTACCGGATAAGAAAATACAGCTTATCGTCAACAACGACCAAATTG
TGGCACACCAATAG

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (204-335)

• AAA lid domain (AAA_lid_9) (342-444)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

3D structure

• AlphaFold DB: Q8DEV2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.828	100	0.474
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.54	100	0.415
clpE	Streptococcus mutans UA159	48.159	79.23	0.382
clpE	Streptococcus pneumoniae D39	48.154	78.996	0.38
clpE	Streptococcus pneumoniae Rx1	48.154	78.996	0.38
clpE	Streptococcus pneumoniae R6	48.154	78.996	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	46.009	80.397	0.37