Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   CCD81_RS08615 Genome accession   NZ_CP021523
Coordinates   1537924..1538784 (+) Length   286 a.a.
NCBI ID   WP_002216403.1    Uniprot ID   A0A9K2PRG6
Organism   Neisseria meningitidis strain 98-182     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1532924..1543784
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCD81_RS08595 (CCD81_08800) dapD 1533477..1534298 (-) 822 WP_002228980.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  CCD81_RS08605 (CCD81_08810) pgi 1534465..1536108 (-) 1644 WP_002228985.1 glucose-6-phosphate isomerase -
  CCD81_RS08610 (CCD81_08815) pilG 1536618..1537850 (+) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  CCD81_RS08615 (CCD81_08820) pilD 1537924..1538784 (+) 861 WP_002216403.1 A24 family peptidase Machinery gene
  CCD81_RS08620 (CCD81_08825) coaE 1538786..1539418 (+) 633 WP_002226983.1 dephospho-CoA kinase -
  CCD81_RS08625 (CCD81_08830) - 1539411..1539620 (+) 210 WP_002226982.1 DNA gyrase inhibitor YacG -
  CCD81_RS08630 (CCD81_08835) pilF 1539705..1541381 (-) 1677 WP_002228974.1 type IV-A pilus assembly ATPase PilB Machinery gene
  CCD81_RS08650 (CCD81_08845) - 1541871..1542317 (-) 447 WP_002220271.1 DUF441 domain-containing protein -
  CCD81_RS08655 (CCD81_08850) ispB 1542322..1543296 (-) 975 WP_002216396.1 octaprenyl diphosphate synthase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31345.37 Da        Isoelectric Point: 8.2213

>NTDB_id=231843 CCD81_RS08615 WP_002216403.1 1537924..1538784(+) (pilD) [Neisseria meningitidis strain 98-182]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=231843 CCD81_RS08615 WP_002216403.1 1537924..1538784(+) (pilD) [Neisseria meningitidis strain 98-182]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGCAGTTTCTTAAA
CGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGTCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

95.789

99.65

0.955
  pilD Vibrio cholerae strain A1552

44.444

100

0.448
  pilD Acinetobacter baumannii D1279779

47.348

92.308

0.437
  pilD Acinetobacter nosocomialis M2

47.348

92.308

0.437
  pilD Vibrio campbellii strain DS40M4

44.928

96.503

0.434

Multiple sequence alignment