Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   CCD83_RS10310 Genome accession   NZ_CP021521
Coordinates   1803027..1803491 (+) Length   154 a.a.
NCBI ID   WP_010981060.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 09-292     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1803192..1820006 1803027..1803491 flank -299


Gene organization within MGE regions


Location: 1803027..1820006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCD83_RS10310 (CCD83_10500) comE 1803027..1803491 (+) 465 WP_010981060.1 ComEA family DNA-binding protein Machinery gene
  CCD83_RS12770 - 1803603..1803761 (+) 159 WP_033909552.1 hypothetical protein -
  CCD83_RS10320 (CCD83_10505) dnaJ 1803843..1804964 (+) 1122 WP_002215274.1 molecular chaperone DnaJ -
  CCD83_RS10325 (CCD83_10510) - 1805160..1807178 (+) 2019 WP_002230175.1 OPT family oligopeptide transporter -
  CCD83_RS10330 (CCD83_10515) rfbC 1807221..1807778 (-) 558 WP_002228846.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  CCD83_RS10335 (CCD83_10520) rfbA 1807832..1808698 (-) 867 WP_002226897.1 glucose-1-phosphate thymidylyltransferase RfbA -
  CCD83_RS10340 (CCD83_10525) rfbB 1808761..1809843 (-) 1083 WP_002230174.1 dTDP-glucose 4,6-dehydratase -
  CCD83_RS13185 galE 1809844..1810464 (-) 621 Protein_1752 UDP-glucose 4-epimerase GalE -
  CCD83_RS13190 - 1810543..1810887 (-) 345 WP_002228843.1 DNA adenine methylase -
  CCD83_RS13195 - 1810880..1811074 (-) 195 WP_002215282.1 DNA cytosine methyltransferase -
  CCD83_RS10350 (CCD83_10535) - 1811052..1811882 (-) 831 WP_002215283.1 DNA cytosine methyltransferase -
  CCD83_RS10355 (CCD83_10540) - 1811913..1814186 (-) 2274 WP_002230176.1 Tex family protein -
  CCD83_RS10360 (CCD83_10545) - 1814251..1814901 (-) 651 WP_002215285.1 ABC transporter ATP-binding protein -
  CCD83_RS10365 (CCD83_10550) - 1814898..1815695 (-) 798 WP_002215286.1 ABC transporter permease -
  CCD83_RS10370 (CCD83_10555) ctrB 1815695..1816858 (-) 1164 WP_002215287.1 capsule polysaccharide export protein CtrB -
  CCD83_RS10375 (CCD83_10560) ctrA 1816873..1818048 (-) 1176 WP_002215290.1 capsule polysaccharide export outer membrane protein CtrA -
  CCD83_RS10380 (CCD83_10565) neuC 1818183..1819316 (+) 1134 WP_002226892.1 UDP-N-acetylglucosamine 2-epimerase -
  CCD83_RS10385 (CCD83_10570) neuA 1819320..1820006 (+) 687 WP_002215295.1 N-acylneuraminate cytidylyltransferase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16529.75 Da        Isoelectric Point: 10.6993

>NTDB_id=231753 CCD83_RS10310 WP_010981060.1 1803027..1803491(+) (comE) [Neisseria meningitidis strain 09-292]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=231753 CCD83_RS10310 WP_010981060.1 1803027..1803491(+) (comE) [Neisseria meningitidis strain 09-292]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCACCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747

Multiple sequence alignment