Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   CCD86_RS10285 Genome accession   NZ_CP021518
Coordinates   1828611..1829075 (-) Length   154 a.a.
NCBI ID   WP_010981060.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 12-176     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1820219..1835291 1828611..1829075 within 0


Gene organization within MGE regions


Location: 1820219..1835291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCD86_RS10240 (CCD86_10400) - 1820219..1821049 (+) 831 WP_002215283.1 DNA cytosine methyltransferase -
  CCD86_RS12915 - 1821027..1821221 (+) 195 WP_002215282.1 DNA cytosine methyltransferase -
  CCD86_RS10245 (CCD86_10405) - 1821214..1821558 (+) 345 WP_002228843.1 DNA adenine methylase -
  CCD86_RS10250 (CCD86_10410) galE 1821637..1822257 (+) 621 Protein_1751 UDP-glucose 4-epimerase GalE -
  CCD86_RS10255 (CCD86_10415) rfbB 1822258..1823298 (+) 1041 WP_002228842.1 dTDP-glucose 4,6-dehydratase -
  CCD86_RS10260 (CCD86_10420) rfbA 1823404..1824270 (+) 867 WP_002221803.1 glucose-1-phosphate thymidylyltransferase RfbA -
  CCD86_RS10265 (CCD86_10425) rfbC 1824324..1824881 (+) 558 WP_002228846.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  CCD86_RS10270 (CCD86_10430) - 1824924..1826942 (-) 2019 WP_002228844.1 OPT family oligopeptide transporter -
  CCD86_RS10275 (CCD86_10435) dnaJ 1827138..1828259 (-) 1122 WP_002215274.1 molecular chaperone DnaJ -
  CCD86_RS12530 - 1828341..1828499 (-) 159 WP_033909552.1 hypothetical protein -
  CCD86_RS10285 (CCD86_10440) comE 1828611..1829075 (-) 465 WP_010981060.1 ComEA family DNA-binding protein Machinery gene
  CCD86_RS10320 (CCD86_10480) dksA 1834875..1835291 (-) 417 WP_002215267.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16529.75 Da        Isoelectric Point: 10.6993

>NTDB_id=231607 CCD86_RS10285 WP_010981060.1 1828611..1829075(-) (comE) [Neisseria meningitidis strain 12-176]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=231607 CCD86_RS10285 WP_010981060.1 1828611..1829075(-) (comE) [Neisseria meningitidis strain 12-176]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCACCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747
  comE Neisseria gonorrhoeae MS11

94.262

79.221

0.747

Multiple sequence alignment