Detailed information NTG0230294

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: JG10_RS26740
• Genome accession: NZ_CP021380
• Coordinates: 5645115..5646452 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain CCBH4851
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5640115..5651452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JG10_RS26715 (AL347_12195)	pgeF	5640258..5640986 (-)	729	WP_003119426.1	peptidoglycan editing factor PgeF	-
JG10_RS26720 (AL347_12200)	rluD	5640983..5641945 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
JG10_RS26725 (AL347_12205)	-	5642091..5643116 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
JG10_RS26730	-	5643273..5643518 (+)	246	WP_003102591.1	PP0621 family protein	-
JG10_RS26735 (AL347_12215)	pilS	5643508..5645100 (+)	1593	WP_003119425.1	two-component system sensor histidine kinase PilS	Regulator
JG10_RS26740 (AL347_12220)	pilR	5645115..5646452 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
JG10_RS26745 (AL347_12225)	thiO	5646498..5647592 (-)	1095	WP_003119424.1	glycine oxidase ThiO	-
JG10_RS26750 (AL347_12230)	-	5647727..5648236 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
JG10_RS26755 (AL347_12235)	-	5648342..5648848 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
JG10_RS26760 (AL347_12240)	pilV	5648839..5649396 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
JG10_RS26765 (AL347_12245)	pilW	5649393..5650217 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
JG10_RS26770 (AL347_12250)	pilX	5650214..5650801 (+)	588	WP_015648054.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=230294 JG10_RS26740 WP_003094694.1 5645115..5646452(+) (pilR) [Pseudomonas aeruginosa strain CCBH4851]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=230294 JG10_RS26740 WP_003094694.1 5645115..5646452(+) (pilR) [Pseudomonas aeruginosa strain CCBH4851]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384