Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C5L38_RS26300 Genome accession   NZ_CP027022
Coordinates   5786854..5787498 (+) Length   214 a.a.
NCBI ID   WP_062756709.1    Uniprot ID   A0AAV4KJP5
Organism   Streptomyces sp. WAC00288     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5781854..5792498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5L38_RS26280 (C5L38_26285) - 5782553..5783338 (-) 786 WP_062756707.1 transglycosylase SLT domain-containing protein -
  C5L38_RS26285 (C5L38_26290) - 5783615..5784742 (-) 1128 WP_079131259.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  C5L38_RS26290 (C5L38_26295) - 5784739..5785530 (-) 792 WP_079131353.1 SDR family oxidoreductase -
  C5L38_RS26295 (C5L38_26300) - 5785716..5786861 (+) 1146 WP_062756708.1 GAF domain-containing sensor histidine kinase -
  C5L38_RS26300 (C5L38_26305) vraR 5786854..5787498 (+) 645 WP_062756709.1 response regulator transcription factor Regulator
  C5L38_RS26305 (C5L38_26310) - 5787653..5787892 (+) 240 WP_062756710.1 chaplin -
  C5L38_RS26310 (C5L38_26315) - 5787975..5788766 (-) 792 WP_062756711.1 hypothetical protein -
  C5L38_RS26315 (C5L38_26320) - 5788903..5789700 (+) 798 WP_030204886.1 ABC transporter ATP-binding protein -
  C5L38_RS26320 (C5L38_26325) - 5789772..5790203 (+) 432 WP_062756712.1 NfeD family protein -
  C5L38_RS26325 (C5L38_26330) - 5790297..5791235 (+) 939 WP_062756713.1 SPFH domain-containing protein -
  C5L38_RS26330 (C5L38_26335) - 5791334..5792101 (+) 768 WP_062756714.1 sulfite exporter TauE/SafE family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23174.49 Da        Isoelectric Point: 5.6849

>NTDB_id=229913 C5L38_RS26300 WP_062756709.1 5786854..5787498(+) (vraR) [Streptomyces sp. WAC00288]
MADKPIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGDEGVARAEELRPDVVLMDVKMPGTDGIEALKRLRELANPA
RVLIVTSFTEQRTVVPALRAGASGYVYKDIDPDALAGAIRSVHAGHVLLQPEVAGALLSQDDAPGGTGRGPSLTEREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGLTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=229913 C5L38_RS26300 WP_062756709.1 5786854..5787498(+) (vraR) [Streptomyces sp. WAC00288]
GTGGCTGACAAGCCCATCCGCGTCCTGCTGGTCGACGACCACCAGGTCGTCCGCCGAGGCCTGCGCACCTTCCTGGAGGT
GCAGGACGACATAGAGGTCGTGGGGGAGGCCTCCGACGGCGACGAGGGCGTCGCCCGCGCCGAGGAGCTCCGCCCCGACG
TCGTCCTCATGGACGTGAAGATGCCCGGTACGGACGGGATCGAGGCCCTGAAGCGGCTCCGCGAGCTCGCCAACCCCGCC
AGGGTCCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTCGTCCCCGCGCTCCGCGCCGGCGCCTCCGGATACGTCTA
CAAGGACATCGACCCCGACGCCCTGGCCGGCGCGATCCGCTCCGTCCACGCCGGACACGTCCTGCTCCAGCCCGAGGTCG
CCGGTGCGCTCCTCTCCCAGGACGACGCCCCCGGCGGTACGGGCCGGGGACCGTCCCTCACCGAACGGGAGCGGGAGGTC
CTCGGCCTGATCGCGGACGGGCGGTCCAACCGCGAGATCGCCCGCGCCCTGGTCCTCTCCGAGAAGACGGTCAAGACGCA
CGTCTCGAACATCCTGATGAAGCTCGACCTCGCGGACCGAACCCAGGCGGCCCTCTGGGCGGTGCGCCACGGCCTCACCC
GCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AAV4KJP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.498

97.664

0.435
  degU Bacillus subtilis subsp. subtilis str. 168

40.271

100

0.416