Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C5L38_RS23575 Genome accession   NZ_CP027022
Coordinates   5190715..5191395 (-) Length   226 a.a.
NCBI ID   WP_062756000.1    Uniprot ID   A0AAV4KPN0
Organism   Streptomyces sp. WAC00288     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5185715..5196395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5L38_RS23550 (C5L38_23555) - 5185968..5186798 (-) 831 WP_062755988.1 serine hydrolase domain-containing protein -
  C5L38_RS23555 (C5L38_23560) - 5186860..5187264 (+) 405 WP_062755990.1 MerR family transcriptional regulator -
  C5L38_RS23560 (C5L38_23565) - 5187261..5188286 (+) 1026 WP_062755992.1 aldo/keto reductase -
  C5L38_RS23565 (C5L38_23570) - 5188322..5189536 (-) 1215 WP_062755995.1 acyltransferase -
  C5L38_RS23570 (C5L38_23575) - 5189533..5190513 (-) 981 WP_062755998.1 alpha/beta hydrolase -
  C5L38_RS23575 (C5L38_23580) vraR 5190715..5191395 (-) 681 WP_062756000.1 response regulator transcription factor Regulator
  C5L38_RS23580 (C5L38_23585) - 5191392..5192837 (-) 1446 WP_229991667.1 sensor histidine kinase -
  C5L38_RS23585 (C5L38_23590) - 5192971..5194050 (-) 1080 WP_062756002.1 DUF4429 domain-containing protein -
  C5L38_RS23590 (C5L38_23595) - 5194107..5195327 (-) 1221 WP_062756005.1 alpha/beta hydrolase -
  C5L38_RS23595 (C5L38_23600) - 5195464..5196120 (-) 657 WP_062756007.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24034.78 Da        Isoelectric Point: 5.1128

>NTDB_id=229907 C5L38_RS23575 WP_062756000.1 5190715..5191395(-) (vraR) [Streptomyces sp. WAC00288]
MTIRVIIVDDQAMVRAGFAALLAAQPDIDVVGEAPDGLRGVEVARSAHPDVVLMDVRMPELDGLAAAREILHPPAGVTHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGEALLAPSVTRRLIADFAASRPAPRRDTAALRLNG
LTPRETEVLELIARGLSNQEIAESLVLAEQTVKTHIGRVLAKLDLRDRAQAVVFAYESGLVTPGSA

Nucleotide


Download         Length: 681 bp        

>NTDB_id=229907 C5L38_RS23575 WP_062756000.1 5190715..5191395(-) (vraR) [Streptomyces sp. WAC00288]
GTGACCATCCGCGTCATCATCGTCGACGACCAGGCCATGGTGCGGGCCGGTTTCGCCGCGCTGCTCGCCGCGCAGCCCGA
CATCGACGTCGTCGGCGAGGCCCCGGACGGGCTGCGGGGCGTGGAGGTGGCCCGGTCGGCGCACCCGGACGTGGTCCTCA
TGGACGTGCGGATGCCCGAGCTGGACGGGCTCGCGGCGGCGCGCGAGATCCTGCACCCGCCGGCCGGGGTCACGCACCGG
CCGAAGGTGCTGATGCTGACCACCTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCGGGCGCGTCCGGCTTCCT
CCTCAAGGACGCGCCGCCGGCCGACCTGATCGCGGCGGTACGGGTGGTGGCGGCGGGCGAGGCGCTGCTCGCCCCGTCCG
TGACCCGCCGTCTGATCGCCGACTTCGCCGCGTCCCGCCCGGCCCCGCGCCGGGACACCGCGGCGCTGCGCCTGAACGGT
CTCACCCCGCGCGAGACGGAGGTCCTGGAGCTGATCGCCCGGGGCCTGTCCAACCAGGAGATCGCGGAGAGCCTGGTCCT
CGCCGAGCAGACGGTGAAGACCCACATCGGCCGGGTCCTGGCCAAGCTGGACCTGCGCGACCGGGCCCAGGCGGTGGTCT
TCGCGTACGAGTCGGGGCTCGTGACGCCGGGTTCGGCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-215)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AAV4KPN0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.819

97.788

0.389
  degU Bacillus subtilis subsp. subtilis str. 168

37.991

100

0.385

Multiple sequence alignment