Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C5L38_RS14375 Genome accession   NZ_CP027022
Coordinates   3179312..3179974 (-) Length   220 a.a.
NCBI ID   WP_062753021.1    Uniprot ID   A0AAV4KG75
Organism   Streptomyces sp. WAC00288     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3174312..3184974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5L38_RS14350 (C5L38_14355) - 3174370..3175110 (-) 741 WP_062753011.1 helix-turn-helix domain-containing protein -
  C5L38_RS14355 (C5L38_14360) - 3175352..3176014 (+) 663 WP_062753013.1 DUF4097 family beta strand repeat-containing protein -
  C5L38_RS14360 (C5L38_14365) - 3176057..3177040 (+) 984 WP_062753015.1 ATP-binding cassette domain-containing protein -
  C5L38_RS14365 (C5L38_14370) - 3177037..3177825 (+) 789 WP_062753017.1 ABC transporter permease -
  C5L38_RS14370 (C5L38_14375) - 3177858..3179201 (-) 1344 WP_062753019.1 PAS domain-containing protein -
  C5L38_RS14375 (C5L38_14380) vraR 3179312..3179974 (-) 663 WP_062753021.1 response regulator transcription factor Regulator
  C5L38_RS14380 (C5L38_14385) - 3180065..3181567 (-) 1503 WP_079131080.1 histidine kinase -
  C5L38_RS14385 (C5L38_14390) - 3181675..3182631 (+) 957 WP_062753023.1 ATP-binding cassette domain-containing protein -
  C5L38_RS14390 (C5L38_14395) - 3182628..3183368 (+) 741 WP_062756937.1 ABC transporter permease -
  C5L38_RS14395 (C5L38_14400) pdxH 3183664..3184293 (-) 630 WP_229991434.1 pyridoxamine 5'-phosphate oxidase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23578.09 Da        Isoelectric Point: 5.1781

>NTDB_id=229876 C5L38_RS14375 WP_062753021.1 3179312..3179974(-) (vraR) [Streptomyces sp. WAC00288]
MPITVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQRRPDVVAMDVRMPLMDGIEATRAVLRTVHEPPKI
LVVTTFENDEYVYGALRAGADGFLLKRARPAEIVHAVRLVAEGDSLLFPAAVRQLAASYGRERDGSEAREALERAGLTER
EADVLRLVARGLSNAEIAARLVVGTETVKSHVSSVLAKLGARDRTQAVIAAYESGFVSPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=229876 C5L38_RS14375 WP_062753021.1 3179312..3179974(-) (vraR) [Streptomyces sp. WAC00288]
ATGCCGATCACCGTCCTCCTCGTCGACGACGAACCGCTGGTCCGGGCCGGTCTGCGCGCCGTCCTGGAGGCGCAGCCCGA
CATCGAGGTGGTGGGCGAGGCGGCCGACGGGGCCGCCGTCATCCCCCTCGTGCGCCAACGGCGCCCCGACGTCGTCGCGA
TGGACGTCCGCATGCCGCTGATGGACGGCATCGAGGCGACCCGCGCGGTCCTGCGCACGGTGCACGAGCCGCCGAAGATC
CTGGTCGTCACCACCTTCGAGAACGACGAGTACGTGTACGGGGCGCTGCGCGCGGGCGCCGACGGCTTCCTGCTCAAGCG
GGCCCGCCCGGCGGAGATCGTGCACGCGGTGCGCCTCGTGGCGGAGGGCGACTCGCTCCTCTTCCCGGCGGCGGTACGGC
AGTTGGCCGCCTCGTACGGGCGGGAGCGGGACGGGTCGGAGGCCCGGGAGGCGCTGGAACGGGCCGGCCTCACCGAGCGG
GAGGCGGACGTGCTGCGGCTCGTGGCGCGCGGCCTGTCGAACGCGGAGATCGCCGCGCGCCTGGTGGTGGGCACGGAGAC
GGTGAAGTCGCACGTCAGCTCCGTCCTGGCGAAGCTCGGCGCCCGCGACCGCACCCAGGCGGTCATCGCCGCCTACGAGT
CGGGCTTCGTCTCACCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AAV4KG75

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.014

98.636

0.405
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.364